Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | IL17A | Q16552 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | SCN1A | P35498 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13103802 | 0.84 | POLB (0.48) | EPHX2ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL2375260 | 0.83 | SIGMAR1 (0.46) | EPHX2SIGMAR1ALDH1A1HRH3MAPK1 | |
| SCHEMBL24737221 | 0.83 | HTR7 (0.49) | SIGMAR1ALDH1A1POLBSMN1; SMN2HTR7 | |
| SCHEMBL11440371 | 0.83 | HTR7 (0.53) | SIGMAR1KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL24518600 | 0.81 | SIGMAR1 (0.57) | SIGMAR1L3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL6653067 | 0.80 | CYP3A4 (0.47) | L3MBTL1ALDH1A1CYP1A2GAAHPGD | |
| SCHEMBL10591990 | 0.79 | CYP2A6 (0.42) | ALDH1A1GAAHPGDSMN1; SMN2HTR7 | |
| SCHEMBL19623616 | 0.79 | ALDH1A1 (0.42) | KMT2AMEN1ALDH1A1MAPK1CYP1A2 | |
| SCHEMBL2377976 | 0.77 | MAPT (0.55) | SIGMAR1KMT2AMEN1ALDH1A1KCNH2 | |
| SCHEMBL3229035 | 0.77 | ALDH1A1 (0.44) | KMT2AALDH1A1KCNH2POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11365196-B2 | FGFR inhibitor and application thereof | BETTA PHARMACEUTICALS CO., LTD. (CN) | 2022-06-21 | — | — | US | disclosed |
| US-20210130353-A1 | FGFR INHIBITOR AND APPLICATION THEREOF | BETTA PHARMACEUTICALS CO., LTD. (CN) | 2021-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11365196-B2 | FGFR inhibitor and application thereof | FGFR1, FGFR4, FGFR2 | EPHX2 2589/4885SIGMAR1 4734/4885L3MBTL1 3103/4885 |
| US-20210130353-A1 | FGFR INHIBITOR AND APPLICATION THEREOF | FGFR1, FGFR4, FGFR2 | EPHX2 2613/4885SIGMAR1 4694/4885L3MBTL1 3437/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.