Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 9/20 | 0.53 |
| ▸ | IDO1 | P14902 | 4/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.41 |
| ▸ | AXL | P30530 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18398743 | 0.78 | IDO1 (0.55) | METAP2IDO1HSP90AA1CDK2NOS1 | |
| SCHEMBL10594265 | 0.78 | NOS1 (0.53) | METAP2IDO1TRPA1HSP90AA1CDK2 | |
| SCHEMBL24131026 | 0.78 | METAP2 (0.51) | METAP2IDO1TRPA1 | |
| SCHEMBL24131138 | 0.78 | TRPA1 (0.50) | METAP2IDO1TRPA1CDK2 | |
| SCHEMBL24536500 | 0.76 | METAP2 (0.53) | METAP2IDO1TRPA1HSP90AA1CDK2 | |
| SCHEMBL8404433 | 0.75 | IDO1 (0.63) | METAP2IDO1TRPA1NOS1CYP1A2 | |
| SCHEMBL2144932 | 0.73 | IDO1 (0.47) | METAP2IDO1TRPA1CDK2NOS1 | |
| SCHEMBL10594464 | 0.73 | TRPA1 (0.46) | METAP2IDO1TRPA1HSP90AA1CDK2 | |
| SCHEMBL16646932 | 0.72 | IDO1 (0.50) | METAP2IDO1TRPA1NOS1CYP1A2 | |
| SCHEMBL1709837 | 0.72 | IDO1 (0.61) | METAP2IDO1NOS1AXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4871653-A | DEVELOPING IN PRESENCE OF MERCAPTO POLYAZAINDENE PROMOTERS AND NUCLEATING QUATERNARY OR HYDRAZIDE-TYPE COMPOUNDS | FUJI PHOTO FILM CO., LTD. (JP) | 1989-10-03 | — | — | US | disclosed |
| EP-0146302-A1 | Light-sensitive silver halide photographic material for direct-post and method for processing the same | KONICA CORPORATION (JP) | 1985-06-26 | — | — | EP | disclosed |