Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 9/20 | 0.51 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.47 |
| ▸ | IDO1 | P14902 | 7/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10594461 | 0.78 | METAP2 (0.53) | METAP2TRPA1IDO1 | |
| SCHEMBL25081099 | 0.75 | IDO1 (0.56) | METAP2TRPA1IDO1 | |
| SCHEMBL23338155 | 0.75 | METAP2 (0.58) | METAP2TRPA1IDO1 | |
| SCHEMBL16675976 | 0.74 | METAP2 (0.49) | METAP2TRPA1IDO1 | |
| SCHEMBL681910 | 0.74 | METAP2 (0.49) | METAP2TRPA1IDO1 | |
| SCHEMBL26302437 | 0.73 | METAP2 (0.52) | METAP2TRPA1IDO1 | |
| SCHEMBL18398743 | 0.73 | IDO1 (0.55) | METAP2IDO1 | |
| SCHEMBL10594265 | 0.73 | NOS1 (0.53) | METAP2TRPA1IDO1 | |
| SCHEMBL2611042 | 0.73 | IDO1 (0.55) | METAP2TRPA1IDO1 | |
| SCHEMBL24131138 | 0.72 | TRPA1 (0.50) | METAP2TRPA1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021258010-A1 | OXIME COMPOUNDS USEFUL AS T CELL ACTIVATORS | GOSSAMER BIO SERVICES, INC. (US) | 2021-12-23 | — | — | WO | disclosed |