Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 6/20 | 0.59 |
| ▸ | METAP2 | P50579 | 4/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | AXL | P30530 | 2/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10594265 | 0.81 | NOS1 (0.53) | NOS1METAP2TRPA1AXLIDO1 | |
| SCHEMBL30234107 | 0.75 | NOS1 (1.00) | NOS1METAP2TRPA1AXLIDO1 | |
| SCHEMBL476854 | 0.75 | NOS1 (1.00) | NOS1METAP2TRPA1AXLIDO1 | |
| SCHEMBL4314318 | 0.75 | NOS1 (1.00) | NOS1METAP2TRPA1AXLIDO1 | |
| SCHEMBL10594556 | 0.74 | NOS1 (0.58) | NOS1METAP2TRPA1MAPK10RIPK1 | |
| SCHEMBL11578011 | 0.71 | NOS1 (0.48) | NOS1METAP2TRPA1AXLCHEK1 | |
| SCHEMBL10595301 | 0.68 | NOS1 (0.63) | NOS1MAPK10RIPK1HPGDPIM3 | |
| SCHEMBL21263642 | 0.68 | IDO1 (0.46) | NOS1METAP2IDO1POLBKMT2A | |
| SCHEMBL10594461 | 0.68 | METAP2 (0.53) | NOS1METAP2TRPA1AXLIDO1 | |
| SCHEMBL14487466 | 0.67 | METAP2 (0.56) | NOS1METAP2IDO1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4871653-A | DEVELOPING IN PRESENCE OF MERCAPTO POLYAZAINDENE PROMOTERS AND NUCLEATING QUATERNARY OR HYDRAZIDE-TYPE COMPOUNDS | FUJI PHOTO FILM CO., LTD. (JP) | 1989-10-03 | — | — | US | disclosed |