Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.61 |
| ▸ | NOS1 | P29475 | 5/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | NOS2 | P35228 | 2/20 | 0.61 |
| ▸ | BLM | P54132 | 2/20 | 0.61 |
| ▸ | THRB | P10828 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | RECQL | P46063 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | APEX1 | P27695 | 1/20 | 0.61 |
| ▸ | NOS3 | P29474 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2702745 | 0.84 | MAPT (0.58) | MAPTNOS1TDP1CYP3A4KDM4E | |
| SCHEMBL10594465 | 0.79 | NOS1 (0.69) | MAPTNOS1TDP1CYP3A4KDM4E | |
| SCHEMBL10595301 | 0.78 | NOS1 (0.63) | MAPTNOS1TDP1CYP3A4KDM4E | |
| 7-Nitroindazole SCHEMBL216995 | 0.77 | NOS1 (1.00) | MAPTNOS1TDP1CYP3A4KDM4E | |
| 7-Nitroindazole SCHEMBL4297993 | 0.75 | NOS1 (0.97) | MAPTNOS1TDP1CYP3A4KDM4E | |
| 7-Nitroindazole SCHEMBL4297994 | 0.75 | NOS1 (0.97) | MAPTNOS1TDP1CYP3A4KDM4E | |
| SCHEMBL30496200 | 0.73 | ALDH1A1 (0.61) | MAPTNOS1TDP1CYP3A4KDM4E | |
| SCHEMBL4717435 | 0.73 | NOS1 (0.64) | MAPTNOS1TDP1CYP3A4KDM4E | |
| SCHEMBL15796932 | 0.71 | NOS1 (0.74) | MAPTNOS1TDP1CYP3A4KDM4E | |
| 7-Nitroindazole SCHEMBL3722668 | 0.70 | NOS1 (0.72) | MAPTNOS1TDP1CYP3A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4871653-A | DEVELOPING IN PRESENCE OF MERCAPTO POLYAZAINDENE PROMOTERS AND NUCLEATING QUATERNARY OR HYDRAZIDE-TYPE COMPOUNDS | FUJI PHOTO FILM CO., LTD. (JP) | 1989-10-03 | — | — | US | disclosed |