Sugi Predict

Sugi Predict / Compounds / SCHEMBL1059672

SCHEMBL1059672

SCHEMBL1059672

CC1(C)O[C@H]2OC(CO)(COCc3ccccc3)[C@@H](OCc3ccccc3)[C@H]2O1

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 1/20 0.37
▸ MEN1 O00255 1/20 0.34
▸ KMT2A Q03164 1/20 0.34
▸ TSHR P16473 1/20 0.33
▸ GSTP1 P09211 2/20 0.32
▸ PDE4D Q08499 2/20 0.32
▸ IDO1 P14902 1/20 0.32
▸ TAAR1 Q96RJ0 1/20 0.32
▸ CHRNB2 P17787 1/20 0.31
▸ CHRNB4 P30926 1/20 0.31
▸ CHRNA3 P32297 1/20 0.31
▸ CHRNA4 P43681 1/20 0.31
▸ KDM4E B2RXH2 1/20 0.31
▸ POLB P06746 1/20 0.31
▸ GLB1 P16278 1/20 0.30
▸ TACR1 P25103 1/20 0.30
▸ BCHE P06276 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29189662 1.00 ALDH1A1 (0.37) ALDH1A1MEN1KMT2ATSHRGSTP1
SCHEMBL20406042 1.00 ALDH1A1 (0.37) ALDH1A1MEN1KMT2ATSHRGSTP1
SCHEMBL13382976 1.00 ALDH1A1 (0.37) ALDH1A1MEN1KMT2ATSHRGSTP1
SCHEMBL24498686 1.00 ALDH1A1 (0.37) ALDH1A1MEN1KMT2ATSHRGSTP1
SCHEMBL18999217 1.00 ALDH1A1 (0.37) ALDH1A1MEN1KMT2ATSHRGSTP1
SCHEMBL24371819 1.00 ALDH1A1 (0.37) ALDH1A1MEN1KMT2ATSHRGSTP1
SCHEMBL2512944 1.00 ALDH1A1 (0.37) ALDH1A1MEN1KMT2ATSHRGSTP1
SCHEMBL19221818 1.00 ALDH1A1 (0.37) ALDH1A1MEN1KMT2ATSHRGSTP1
SCHEMBL21063154 1.00 ALDH1A1 (0.37) ALDH1A1MEN1KMT2ATSHRGSTP1
SCHEMBL1096431 1.00 ALDH1A1 (0.37) ALDH1A1MEN1KMT2ATSHRGSTP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4015005-A1 MODIFIED NUCLEOSIDES, NUCLEOTIDES, AND NUCLEIC ACIDS, AND USES THEREOF ModernaTX, Inc. (US) 2022-06-22 — — EP disclosed
EP-3682905-B1 MODIFIED NUCLEOSIDES, NUCLEOTIDES, AND NUCLEIC ACIDS, AND USES THEREOF MODERNATX INC (US) 2021-12-01 — — EP disclosed
US-20210308283-A1 MODIFIED NUCLEOSIDES, NUCLEOTIDES, AND NUCLEIC ACIDS, AND USES THEREOF MODERNA THERAPEUTICS, INC. 2021-10-07 — — US disclosed
EP-3682905-A1 MODIFIED NUCLEOSIDES, NUCLEOTIDES, AND NUCLEIC ACIDS, AND USES THEREOF ModernaTX, Inc. (US) 2020-07-22 — — EP disclosed
EP-3492109-B1 MODIFIED NUCLEOSIDES, NUCLEOTIDES, AND NUCLEIC ACIDS, AND USES THEREOF MODERNATX INC (US) 2020-03-04 — — EP disclosed
EP-3492109-A1 MODIFIED NUCLEOSIDES, NUCLEOTIDES, AND NUCLEIC ACIDS, AND USES THEREOF Moderna Therapeutics, Inc. (US) 2019-06-05 — — EP disclosed
EP-1152009-B2 NOVEL NUCLEOSIDES AND OLIGONUCLEOTIDE ANALOGUES DAIICHI SANKYO CO LTD (JP) 2017-09-06 — — EP disclosed
US-20170056528-A1 MODIFIED NUCLEOSIDES, NUCLEOTIDES, AND NUCLEIC ACIDS, AND USES THEREOF MODERNATX, INC. 2017-03-02 — — US disclosed
US-8957201-B2 Oligonucleotide analogues and methods utilizing the same DAIICHI SANKYO COMPANY, LIMITED (JP) 2015-02-17 — — US disclosed
US-20110009471-A1 Oligonucleotide analogues and methods utilizing the same DAIICHI SANKYO COMPANY, LIMITED (JP) 2011-01-13 — — US disclosed
US-7816333-B2 Oligonucleotide analogues and methods utilizing the same DAIICHI SANKYO COMPANY, LIMITED (JP) 2010-10-19 — — US disclosed
US-20090149404-A1 Oligonucleotide analogues and methods utilizing the same DAIICHI SANKYO COMPANY, LIMITED (JP) 2009-06-11 — — US disclosed
US-7335765-B2 Nucleoside and oligonucleotide analogues DAIICHI SANKYO COMPANY, LIMITED (JP) 2008-02-26 — — US disclosed
US-7314923-B2 Nucleoside and oligonucleotide analogues DAIICHI SANKYO COMPANY, LIMITED (JP) 2008-01-01 — — US disclosed
EP-1152009-B1 NOVEL NUCLEOSIDES AND OLIGONUCLEOTIDE ANALOGUES SANKYO CO (JP) 2005-01-26 — — EP disclosed
US-20030207841-A1 Novel nucleoside and oligonucleotide analogues SANKYO COMPANY LIMITED (JP) 2003-11-06 — — US disclosed
US-20020147332-A1 Novel nucleoside and oligonucleotide analogues SANKYO COMPANY, LIMITED (JP) 2002-10-10 — — US disclosed
EP-1152009-A1 NOVEL NUCLEOSIDES AND OLIGONUCLEOTIDE ANALOGUES Sankyo Company, Limited (JP) 2001-11-07 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210308283-A1 MODIFIED NUCLEOSIDES, NUCLEOTIDES, AND NUCLEIC ACIDS, AND USES THEREOF ADAR, NT5C3B, NSUN2 ALDH1A1 2620/4885MEN1 2176/4885KMT2A 1675/4885
US-20170056528-A1 MODIFIED NUCLEOSIDES, NUCLEOTIDES, AND NUCLEIC ACIDS, AND USES THEREOF ADAR, NT5C3B, NSUN2 ALDH1A1 2620/4885MEN1 2176/4885KMT2A 1675/4885
US-20110009471-A1 Oligonucleotide analogues and methods utilizing the same NSUN2, RNGTT, DUT ALDH1A1 1693/4885MEN1 1348/4885KMT2A 1809/4885
US-20020147332-A1 Novel nucleoside and oligonucleotide analogues RNGTT, NSUN2, MTAP ALDH1A1 1208/4885MEN1 2596/4885KMT2A 2679/4885
US-20090149404-A1 Oligonucleotide analogues and methods utilizing the same NSUN2, RNGTT, DUT ALDH1A1 1693/4885MEN1 1348/4885KMT2A 1809/4885
US-20030207841-A1 Novel nucleoside and oligonucleotide analogues RNGTT, NSUN2, MTAP ALDH1A1 1208/4885MEN1 2596/4885KMT2A 2679/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.