Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 16/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10504510 | 1.00 | ADRB1 (0.39) | ADRB1ADRB2ADRB3KDM4EMEN1 | |
| SCHEMBL10504347 | 0.81 | ADRB1 (0.41) | ADRB1ADRB2ADRB3KDM4EMEN1 | |
| SCHEMBL10505428 | 0.81 | ADRB1 (0.41) | ADRB1ADRB2ADRB3KDM4EMEN1 | |
| SCHEMBL10505259 | 0.75 | ADRB1 (0.36) | ADRB1ADRB2ADRB3KDM4EMEN1 | |
| SCHEMBL10504605 | 0.75 | ADRB3 (0.53) | ADRB1ADRB2ADRB3KDM4EKMT2A | |
| SCHEMBL10505254 | 0.73 | ADRB1 (0.35) | ADRB1ADRB2ADRB3KDM4EMEN1 | |
| SCHEMBL10503738 | 0.72 | HTR1A (0.36) | ADRB1ADRB2ADRB3MEN1CYP1A2 | |
| SCHEMBL10505437 | 0.72 | HTR1A (0.35) | ADRB1ADRB2ADRB3 | |
| SCHEMBL10504207 | 0.71 | HTR1A (0.35) | ADRB1ADRB2ADRB3 | |
| SCHEMBL10503645 | 0.71 | ADRB2 (0.34) | ADRB1ADRB2ADRB3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4863949-A | CARDIOVASCULAR DISORDER TREATMENT | BOEHRINGER MANNHEIM GMBH (DE) | 1989-09-05 | — | — | US | disclosed |
| EP-0200915-A1 | Aminopropanol derivatives, process for their preparation, their use and medicines containing them | Roche Diagnostics GmbH (DE) | 1986-11-12 | — | — | EP | disclosed |