Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A1 | O15245 | 3/20 | 0.69 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.63 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL346989 | 0.97 | SLC22A1 (0.73) | SLC22A1DNM1SLC22A2TSHRALDH1A1 | |
| SCHEMBL7553616 | 0.93 | SLC22A1 (0.69) | SLC22A1DNM1SLC22A2TSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL5084823 | 0.93 | SLC22A1 (0.69) | SLC22A1DNM1SLC22A2TSHRALDH1A1 | |
| Iodide SCHEMBL4333792 | 0.93 | SLC22A1 (0.69) | SLC22A1DNM1SLC22A2TSHRALDH1A1 | |
| SCHEMBL10598485 | 0.93 | SLC22A1 (0.69) | SLC22A1DNM1SLC22A2TSHRALDH1A1 | |
| Water SCHEMBL1332993 | 0.93 | SLC22A1 (0.69) | SLC22A1DNM1SLC22A2TSHRALDH1A1 | |
| Bromide SCHEMBL3680180 | 0.93 | SLC22A1 (0.69) | SLC22A1DNM1SLC22A2TSHRALDH1A1 | |
| SCHEMBL5354508 | 0.90 | SLC22A1 (0.65) | SLC22A1DNM1SLC22A2TSHRALDH1A1 | |
| SCHEMBL11806867 | 0.90 | DNM1 (0.78) | SLC22A1DNM1SLC22A2TSHRALDH1A1 | |
| SCHEMBL16649092 | 0.90 | DNM1 (0.78) | SLC22A1DNM1SLC22A2TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0179031-B1 | METHOD FOR THE SYNTHESIS OF PHARMACOLOGICALLY ACTIVE ARYLOXYPROPANOL AMINE COMPOUNDS | Aktiebolaget Hässle (SE) | 1989-01-18 | — | — | EP | disclosed |
| US-4777293-A | Method for the synthesis of pharmacologically active compounds and intermediates for such synthesis | AKTIEBOLAGET HASSLE (SE) | 1988-10-11 | — | — | US | disclosed |
| EP-0179031-A2 | Method for the synthesis of pharmacologically active aryloxypropanol amine compounds | Aktiebolaget Hässle (SE) | 1986-04-23 | — | — | EP | disclosed |