Hydrochloric Acid

Hydrochloric Acid

SCHEMBL5084823

CCCC[N+](CC)(CCCC)CCCC.[Cl-]

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SLC22A1 O15245 3/20 0.69
DNM1 Q05193 5/20 0.63
SLC22A2 O15244 1/20 0.59
TSHR P16473 2/20 0.53
ALDH1A1 P00352 1/20 0.53
TP53 P04637 1/20 0.53
CYP3A4 P08684 1/20 0.53
ALOX15 P16050 1/20 0.53
ALOX12 P18054 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
HIF1A Q16665 1/20 0.53
HSD17B10 Q99714 1/20 0.53
KDM4E B2RXH2 1/20 0.50
PMP22 Q01453 1/20 0.50
ATM Q13315 1/20 0.50
NFKB1 P19838 1/20 0.44
KCNA1 Q09470 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL346989 0.97 SLC22A1 (0.73) SLC22A1DNM1SLC22A2TSHRALDH1A1
Water SCHEMBL1332993 0.93 SLC22A1 (0.69) SLC22A1DNM1SLC22A2TSHRALDH1A1
Bromide SCHEMBL3680180 0.93 SLC22A1 (0.69) SLC22A1DNM1SLC22A2TSHRALDH1A1
Hydrochloric Acid SCHEMBL394062 0.93 DNM1 (0.72) SLC22A1DNM1SLC22A2TSHRALDH1A1
Iodide SCHEMBL4333792 0.93 SLC22A1 (0.69) SLC22A1DNM1SLC22A2TSHRALDH1A1
Hydrochloric Acid SCHEMBL4131094 0.93 SLC22A1 (0.69) SLC22A1DNM1SLC22A2TSHRALDH1A1
SCHEMBL10598485 0.93 SLC22A1 (0.69) SLC22A1DNM1SLC22A2TSHRALDH1A1
SCHEMBL10598482 0.93 SLC22A1 (0.69) SLC22A1DNM1SLC22A2TSHRALDH1A1
Hydrochloric Acid SCHEMBL8735491 0.91 DNM1 (0.79) SLC22A1DNM1SLC22A2TSHRALDH1A1
SCHEMBL11806867 0.90 DNM1 (0.78) SLC22A1DNM1SLC22A2TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0262305-B1 METHOD FOR THE PREPARATION OF ANILINOFUMARATE AND QUINOLINE-2,3-DICARBOXYLIC ACID AMERICAN CYANAMID COMPANY (US) 1990-10-31 EP claimed
EP-0262305-A1 Method for the preparation of anilinofumarate and quinoline-2,3-dicarboxylic acid AMERICAN CYANAMID COMPANY (US) 1988-04-06 EP claimed
US-4252985-A Process for the preparation of o-methallyloxyphenol by the selective monoetherification of pyrocatechol PHILAGRO (FR) 1981-02-24 US claimed
EP-3724193-A1 PROCESS FOR PREPARING 2-EXO-(2-METHYLBENZYLOXY)-1-METHYL-4-ISOPROPYL-7-OXABICYCLO[2.2.1]HEPTANE BASF Agro B.V. (NL) 2020-10-21 EP disclosed
WO-2019115347-A1 PROCESS FOR PREPARING 2-EXO-(2-METHYLBENZYLOXY)-1-METHYL-4-ISOPROPYL-7-OXABICYCLO[2.2.1]HEPTANE BASF Agro B.V. (NL) 2019-06-20 WO disclosed
US-10259919-B2 Perchlorate ion permselective membranes UNIVERSITY OF DELAWARE (US) 2019-04-16 US disclosed
CN-106478423-B Synthesize N, the method for N- diisopropylethylamine 杭州新德环保科技有限公司 2018-10-02 CN disclosed
US-20170306115-A1 PERCHLORATE ION PERMSELECTIVE MEMBRANES UNIVERSITY OF DELAWARE (US) 2017-10-26 US disclosed
CN-106478423-A Synthesis N, the method for N diisopropylethylamine 杭州新德环保科技有限公司 2017-03-08 CN disclosed
EP-2495229-B1 LOW-MOLECULAR COMPOUND, POLYMER, MATERIAL FOR ELECTRONIC DEVICES, COMPOSITION FOR ELECTRONIC DEVICES, ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC SOLAR CELL ELEMENT, DISPLAY AND LIGHTING EQUIPMENT MITSUBISHI CHEM CORP (JP) 2016-06-01 EP disclosed
WO-2016040067-A1 PERCHLORATE ION PERMSELECTIVE MEMBRANES UNIVERSITY OF DELAWARE (US) 2016-03-17 WO disclosed
US-4503226-A QUATERNARY AMMONIUM CARBOXYLATE CATALYST OLIN CORPORATION (US) 1985-03-05 US disclosed
US-4479006-A PHOSGENATION OF 3-(3,5-DFICHLOROPHENYL)HYDANTOIN AND REACTION OF PRODUCT WITH AN AMINE RHONE-POULENC AGROCHIMIE (FR) 1984-10-23 US disclosed
EP-0004606-B1 PROCESS FOR PREPARING ANILINE COMPOUNDS ETHYL CORPORATION (US) 1982-03-10 EP disclosed
US-4252985-A Process for the preparation of o-methallyloxyphenol by the selective monoetherification of pyrocatechol PHILAGRO (FR) 1981-02-24 US disclosed
US-4186147-A DISPLACEMENT OF THIOCYANOANILINE WITH AN ALCOHOL TO FORM THIOALKYL ANILINE ETHYL CORPORATION (US) 1980-01-29 US disclosed
EP-0004606-A2 Process for preparing aniline compounds ETHYL CORPORATION (US) 1979-10-17 EP disclosed
US-4022816-A TRIALKYL AMMONIUM OR PHOSPHONIUM CATALYST ETHYL CORPORATION (US) 1977-05-10 US disclosed
US-4009116-A Process of preparing substantially organic waste liquids containing radioactive or toxic substances for safe, non-pollutive handling, transportation and permanent storage BAYER AKTIENGESELLSCHAFT (DT) 1977-02-22 US disclosed
US-3960762-A Production of absorbents BAYER AKTIENGESELLSCHAFT (DT) 1976-06-01 US disclosed