Known targets — ChEMBL curated mechanism
GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQ
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A1 | O15245 | 3/20 | 0.69 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.63 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL346989 | 0.97 | SLC22A1 (0.73) | SLC22A1DNM1SLC22A2TSHRALDH1A1 | |
| Water SCHEMBL8910658 | 0.94 | DNM1 (0.74) | SLC22A1DNM1SLC22A2TSHRALDH1A1 | |
| Water SCHEMBL18549325 | 0.94 | SLC22A1 (0.61) | SLC22A1DNM1SLC22A2TSHRALDH1A1 | |
| Water SCHEMBL18549364 | 0.94 | SLC22A1 (0.61) | SLC22A1DNM1SLC22A2TSHRALDH1A1 | |
| Iodide SCHEMBL4333792 | 0.93 | SLC22A1 (0.69) | SLC22A1DNM1SLC22A2TSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL5084823 | 0.93 | SLC22A1 (0.69) | SLC22A1DNM1SLC22A2TSHRALDH1A1 | |
| SCHEMBL10598482 | 0.93 | SLC22A1 (0.69) | SLC22A1DNM1SLC22A2TSHRALDH1A1 | |
| Bromide SCHEMBL3680180 | 0.93 | SLC22A1 (0.69) | SLC22A1DNM1SLC22A2TSHRALDH1A1 | |
| SCHEMBL10598485 | 0.93 | SLC22A1 (0.69) | SLC22A1DNM1SLC22A2TSHRALDH1A1 | |
| Water SCHEMBL3304283 | 0.93 | SLC22A1 (0.69) | SLC22A1DNM1SLC22A2TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 207 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250026960-A1 | POLISHING SLURRY COMPOSITION | KCTECH CO.,LTD. (KR) | 2025-01-23 | — | — | US | claimed |
| CN-119126507-A | Photoresist stripping liquid, preparation method and application thereof | 浙江奥首材料科技有限公司 | 2024-12-13 | — | — | CN | claimed |
| US-12054578-B2 | Process for producing porous materials | AEROGEL-IT GMBH (DE) | 2024-08-06 | — | — | US | claimed |
| CN-118339245-A | Polishing slurry composition | 凯斯科技股份有限公司 | 2024-07-12 | — | — | CN | claimed |
| WO-2023121037-A1 | POLISHING SLURRY COMPOSITION | 주식회사 케이씨텍 | 2023-06-29 | — | — | WO | claimed |
| CN-110914326-B | Method for producing porous material | 埃力格-伊特有限责任公司 | 2023-06-13 | — | — | CN | claimed |
| US-20220098384-A1 | Process for producing porous materials | BASF SE (DE) | 2022-03-31 | — | — | US | claimed |
| EP-3911694-A1 | PROCESS FOR PRODUCING POROUS MATERIALS | BASF SE (DE) | 2021-11-24 | — | — | EP | claimed |
| CN-113430069-A | Low-hydroxylamine water-based cleaning solution, and preparation method and application thereof | 上海新阳半导体材料股份有限公司 | 2021-09-24 | — | — | CN | claimed |
| CN-113430070-A | CoWP-compatible semi-aqueous cleaning solution, and preparation method and application thereof | 上海新阳半导体材料股份有限公司 | 2021-09-24 | — | — | CN | claimed |
| CN-101578556-A | Stripper for coating layer | AZ ELECTRONIC MATERIALS USA (US) | 2009-11-11 | — | — | CN | claimed |
| US-20090120457-A1 | COMPOSITIONS AND METHOD FOR REMOVING COATINGS AND PREPARATION OF SURFACES FOR USE IN METAL FINISHING, AND MANUFACTURING OF ELECTRONIC AND MICROELECTRONIC DEVICES | SURFACE CHEMISTRY DISCOVERIES, INC. (US) | 2009-05-14 | — | — | US | claimed |
| WO-2008081416-A2 | STRIPPER FOR COATING LAYER | AZ ELECTRONIC MATERIALS USA CORP. (DE) | 2008-07-10 | — | — | WO | claimed |
| US-20080161217-A1 | Stripper for Coating Layer | MERCK PATENT GMBH (DE) | 2008-07-03 | — | — | US | claimed |
| CN-1505479-A | Pesticide composition containing oxalic acid | ������ɽ���� | 2004-06-16 | — | — | CN | claimed |
| EP-1389912-A2 | PESTICIDE COMPOSITIONS CONTAINING OXALIC ACID | Monsanto Technology LLC (US) | 2004-02-25 | — | — | EP | claimed |
| WO-2002069718-A2 | PESTICIDE COMPOSITIONS CONTAINING OXALIC ACID | MONSANTO TECHNOLOGY LLC (US) | 2002-09-12 | — | — | WO | claimed |
| US-20020123430-A1 | Pesticide compositions containing oxalic acid | MONSANTO TECHNOLOGY LLC | 2002-09-05 | — | — | US | claimed |
| US-4339501-A | Filter-coated phosphor | TOKYO SHIBAURA DENKI KABUSHIKI KAISHA (JP) | 1982-07-13 | — | — | US | claimed |
| US-4287229-A | BY FORMING A FILM ON SAID PARTICLES FROM A SOLUTION CONTAINING SILICON DIOXIDE AND AN ORGANIC AMMONIUM HYDROXIDE | TOKYO SHIBAURA DENKI KABUSHIKIKAISHA (JP) | 1981-09-01 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020123430-A1 | Pesticide compositions containing oxalic acid | OTC, SLC47A1, SLC47A2 | SLC22A1 292/4885DNM1 1867/4885SLC22A2 323/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.