Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | NQO1 | P15559 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7152597 | 0.84 | ADRA1A (0.63) | KDM4ENQO1EPHX1ADRA2AADRA1A | |
| SCHEMBL10602441 | 0.83 | LTA4H (0.56) | LTA4HNPC1 | |
| SCHEMBL18929969 | 0.82 | NQO1 (0.50) | KDM4ENQO1EPHX1MEN1KMT2A | |
| SCHEMBL5055098 | 0.81 | ADRA2A (0.62) | KDM4ENQO1EPHX1ADRA2AADRA1A | |
| SCHEMBL7784261 | 0.81 | ADRA2A (0.62) | KDM4ENQO1EPHX1ADRA2AADRA1A | |
| SCHEMBL9632245 | 0.80 | ADRA2A (0.45) | KDM4ENQO1EPHX1ADRA2AADRA1A | |
| Hydrochloric Acid SCHEMBL9868612 | 0.80 | MEN1 (0.63) | KDM4ENQO1ADRA2AADRA1AHTT | |
| SCHEMBL28029942 | 0.79 | KDM4E (0.47) | KDM4ENQO1EPHX1HTTMEN1 | |
| SCHEMBL10601381 | 0.79 | TRPA1 (0.39) | HTTTSHRALDH1A1NPC1CYP3A4 | |
| SCHEMBL2498271 | 0.77 | NQO1 (0.59) | KDM4ENQO1EPHX1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0212482-B1 | PROCESS FOR OBTAINING NEGATIVE IMAGES FROM POSITIVE PHOTORESISTS | HOECHST CELANESE CORPORATION (US) | 1989-04-19 | — | — | EP | disclosed |
| EP-0212482-A2 | Process for obtaining negative images from positive photoresists | HOECHST CELANESE CORPORATION (US) | 1987-03-04 | — | — | EP | disclosed |