Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8223272 | 0.89 | THRB (0.51) | NQO1KDM4EMEN1KMT2AHIF1A | |
| SCHEMBL28029942 | 0.85 | KDM4E (0.47) | NQO1KDM4EAKR1C3AKR1C2TSHR | |
| SCHEMBL9946005 | 0.84 | KDM4E (0.50) | NQO1KDM4EAKR1C3AKR1C2TSHR | |
| SCHEMBL10604152 | 0.82 | KDM4E (0.49) | NQO1KDM4EAKR1C3AKR1C2TSHR | |
| SCHEMBL18713791 | 0.80 | ALDH1A1 (0.47) | KDM4ETSHRTDP1MEN1KMT2A | |
| SCHEMBL9945918 | 0.80 | L3MBTL1 (0.46) | KDM4ETSHRTDP1MEN1KMT2A | |
| SCHEMBL16160161 | 0.80 | NQO1 (0.50) | NQO1KDM4EAKR1C3AKR1C2TSHR | |
| SCHEMBL5055098 | 0.79 | ADRA2A (0.62) | NQO1KDM4EAKR1C3AKR1C2TSHR | |
| SCHEMBL7784261 | 0.79 | ADRA2A (0.62) | NQO1KDM4EAKR1C3AKR1C2TSHR | |
| SCHEMBL29657372 | 0.79 | NQO1 (0.59) | NQO1KDM4ETSHRTDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2922841-B1 | ALKYL-AMIDE-SUBSTITUTED PYRIDYL COMPOUNDS USEFUL AS MODULATORS OF IL-12, IL-23 AND/OR IFN ALPHA RESPONSES | BRISTOL MYERS SQUIBB CO (US) | 2017-06-07 | — | — | EP | disclosed |