Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 17/20 | 0.67 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.54 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | MC4R | P32245 | 1/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.54 |
| ▸ | MC3R | P41968 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15856359 | 0.91 | ADRB2 (0.80) | ADRB2ADRB1CYP3A4MAPK1NPSR1 | |
| SCHEMBL11468343 | 0.89 | ADRB2 (0.59) | ADRB2ADRB1CYP3A4NPSR1TSHR | |
| SCHEMBL11468342 | 0.89 | ADRB2 (0.59) | ADRB2ADRB1CYP3A4NPSR1TSHR | |
| SCHEMBL11464953 | 0.87 | LMNA (0.58) | ADRB2ADRB1TSHRHIF1ASLC6A3 | |
| SCHEMBL11464952 | 0.87 | LMNA (0.58) | ADRB2ADRB1TSHRHIF1ASLC6A3 | |
| SCHEMBL11467407 | 0.85 | ADRB2 (0.61) | ADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL11467406 | 0.85 | ADRB2 (0.61) | ADRB2ADRB1ADRB3ALDH1A1 | |
| Bromide SCHEMBL11470045 | 0.84 | ADRB2 (0.59) | ADRB2ADRB1ADRB3ALDH1A1 | |
| Bromide SCHEMBL11470044 | 0.84 | ADRB2 (0.59) | ADRB2ADRB1ADRB3ALDH1A1 | |
| Oxalic Acid SCHEMBL11482348 | 0.82 | SMN1; SMN2 (0.54) | ADRB2ADRB1CYP3A4NPSR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0132595-B1 | TOCOLYTIC AGENT | TPO "PHARMACHIM" (BG) | 1989-06-14 | — | — | EP | disclosed |