Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 3/20 | 0.44 |
| ▸ | REN | P00797 | 2/20 | 0.42 |
| ▸ | METAP2 | P50579 | 7/20 | 0.40 |
| ▸ | METAP1 | P53582 | 4/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9833496 | 1.00 | CTSD (0.44) | CTSDRENMETAP2METAP1CPB2 | |
| SCHEMBL10445670 | 0.88 | REN (0.44) | CTSDRENMETAP2METAP1 | |
| SCHEMBL9833229 | 0.80 | CTSD (0.45) | CTSDRENMETAP2CPB2 | |
| SCHEMBL9831134 | 0.78 | REN (0.51) | CTSDRENMETAP2METAP1CPB2 | |
| SCHEMBL10608625 | 0.78 | REN (0.51) | CTSDRENMETAP2METAP1CPB2 | |
| SCHEMBL7271640 | 0.77 | CTSD (0.49) | CTSDRENMETAP2METAP1CPB2 | |
| SCHEMBL10408931 | 0.77 | CTSD (0.49) | CTSDRENMETAP2METAP1CPB2 | |
| Hydrochloric Acid SCHEMBL9832396 | 0.77 | REN (0.50) | CTSDRENMETAP2METAP1CPB2 | |
| SCHEMBL7326847 | 0.73 | REN (0.46) | CTSDRENMETAP2METAP1CPB2 | |
| SCHEMBL10606277 | 0.73 | CTSD (0.38) | CTSDRENMETAP2METAP1CPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4857507-A | HYPOTENSIVE AGENT | ABBOTT LABORATORIES (US) | 1989-08-15 | — | — | US | disclosed |