Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 3/20 | 0.45 |
| ▸ | REN | P00797 | 2/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | MC4R | P32245 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10606263 | 0.80 | CTSD (0.44) | CTSDRENCPB2METAP2 | |
| SCHEMBL9833496 | 0.80 | CTSD (0.44) | CTSDRENCPB2METAP2 | |
| SCHEMBL9833236 | 0.73 | CTSD (0.37) | CTSDRENCPB2CTSKMETAP2 | |
| SCHEMBL9832812 | 0.72 | REN (0.35) | RENCPB2CTSKMETAP2MMP2 | |
| SCHEMBL9832260 | 0.72 | CTSK (0.36) | RENCTSKMETAP2 | |
| SCHEMBL7589493 | 0.72 | REN (0.35) | RENCTSKMETAP2 | |
| SCHEMBL7051728 | 0.72 | REN (0.35) | RENCTSKMETAP2 | |
| SCHEMBL10608625 | 0.72 | REN (0.51) | CTSDRENCPB2METAP2MMP2 | |
| SCHEMBL9831134 | 0.72 | REN (0.51) | CTSDRENCPB2METAP2MMP2 | |
| SCHEMBL7397008 | 0.72 | EPHX1 (0.49) | CTSDMMP2MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0258289-A4 | PEPTIDE ANALOGS | — | 1991-01-02 | — | — | EP | disclosed |
| US-4857507-A | HYPOTENSIVE AGENT | ABBOTT LABORATORIES (US) | 1989-08-15 | — | — | US | disclosed |
| EP-0258289-A1 | PEPTIDE ANALOGS | ABBOTT LABORATORIES (US) | 1988-03-09 | — | — | EP | disclosed |
| WO-1987004349-A1 | PEPTIDE ANALOGS | DELLARIA JOSEPH | 1987-07-30 | — | — | WO | disclosed |