Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | CDC25B | P30305 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | STAT1 | P42224 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28086833 | 0.93 | NPC1 (0.70) | NPC1POLBKDM4EPTPN1ALDH1A1 | |
| SCHEMBL29467270 | 0.91 | NPC1 (0.68) | NPC1POLBKDM4EPTPN1ALDH1A1 | |
| SCHEMBL2492855 | 0.91 | NPC1 (0.68) | NPC1POLBKDM4EPTPN1ALDH1A1 | |
| SCHEMBL227731 | 0.89 | NPC1 (0.71) | NPC1POLBKDM4EPTPN1ALDH1A1 | |
| SCHEMBL1715918 | 0.89 | NPC1 (0.71) | NPC1POLBKDM4EPTPN1ALDH1A1 | |
| SCHEMBL28325052 | 0.86 | NPC1 (0.62) | NPC1POLBKDM4EPTPN1ALDH1A1 | |
| SCHEMBL10684744 | 0.84 | NPC1 (0.65) | NPC1POLBKDM4EPTPN1ALDH1A1 | |
| SCHEMBL28771676 | 0.83 | NPC1 (0.63) | NPC1POLBKDM4EPTPN1ALDH1A1 | |
| SCHEMBL8048603 | 0.83 | ALDH1A1 (0.61) | NPC1POLBPTPN1ALDH1A1L3MBTL1 | |
| SCHEMBL28529587 | 0.82 | LMNA (0.57) | NPC1POLBKDM4EALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0127203-B1 | NEW PHTHALIDE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND RECORDING SYSTEM UTILIZING THE SAME AS COLOURLESS CHROMOGENIC MATERIAL | KANZAKI PAPER MANUFACTURING CO., LTD (JP) | 1989-06-28 | — | — | EP | disclosed |