Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | CCR6 | P51684 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | STAT1 | P42224 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28325052 | 0.96 | NPC1 (0.62) | LMNASMN1; SMN2MAPTNPC1POLB | |
| SCHEMBL10684744 | 0.95 | NPC1 (0.65) | LMNASMN1; SMN2MAPTNPC1POLB | |
| SCHEMBL28086833 | 0.85 | NPC1 (0.70) | LMNASMN1; SMN2MAPTNPC1POLB | |
| SCHEMBL2323487 | 0.85 | ALDH1A1 (0.64) | LMNASMN1; SMN2MAPTNPC1POLB | |
| SCHEMBL3407551 | 0.85 | HTR6 (0.66) | LMNASMN1; SMN2MAPTPOLBHTT | |
| SCHEMBL9178263 | 0.83 | ALDH1A1 (0.50) | LMNASMN1; SMN2MAPTNPC1POLB | |
| SCHEMBL28578536 | 0.82 | LMNA (0.51) | LMNASMN1; SMN2MAPTNPC1POLB | |
| SCHEMBL11011200 | 0.82 | ALDH1A1 (0.54) | LMNASMN1; SMN2MAPTPOLBHTT | |
| SCHEMBL10607126 | 0.82 | NPC1 (0.62) | LMNASMN1; SMN2MAPTNPC1POLB | |
| SCHEMBL28567564 | 0.81 | ALDH1A1 (0.50) | LMNASMN1; SMN2MAPTNPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112538039-B | Synthetic method of 3-fluoroindolone compound | 福州大学 | 2022-04-22 | — | — | CN | disclosed |
| CN-112538039-A | Synthetic method of 3-fluoroindolone compound | 福州大学 | 2021-03-23 | — | — | CN | disclosed |