Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | STAT1 | P42224 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.54 |
| ▸ | ATM | Q13315 | 3/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | CCR6 | P51684 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28325052 | 0.98 | NPC1 (0.62) | NPC1LMNASMN1; SMN2MAPTPOLB | |
| SCHEMBL28529587 | 0.95 | LMNA (0.57) | NPC1LMNASMN1; SMN2MAPTPOLB | |
| SCHEMBL28086833 | 0.87 | NPC1 (0.70) | NPC1LMNASMN1; SMN2MAPTPOLB | |
| SCHEMBL10607126 | 0.84 | NPC1 (0.62) | NPC1LMNASMN1; SMN2MAPTPOLB | |
| SCHEMBL28578536 | 0.84 | LMNA (0.51) | NPC1LMNASMN1; SMN2MAPTPOLB | |
| SCHEMBL227731 | 0.84 | NPC1 (0.71) | NPC1SMN1; SMN2POLBHTTALDH1A1 | |
| SCHEMBL1715918 | 0.84 | NPC1 (0.71) | NPC1SMN1; SMN2POLBHTTALDH1A1 | |
| SCHEMBL7729876 | 0.84 | SMN1; SMN2 (0.61) | NPC1LMNASMN1; SMN2MAPTHTT | |
| SCHEMBL3407551 | 0.83 | HTR6 (0.66) | LMNASMN1; SMN2MAPTPOLBHTT | |
| SCHEMBL2323487 | 0.83 | ALDH1A1 (0.64) | NPC1LMNASMN1; SMN2MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4528294-A | Benzoyl-phenyl-piperidine derivatives | SOCIETE DE RECHERCHES INDUSTRIELLE S.O.R.I. (FR) | 1985-07-09 | — | — | US | claimed |
| EP-0069012-B1 | BENZOYL-PHENYL-PIPERIDINE DERIVATIVES, THEIR PREPARATION AND MEDICINAL USE | SOCIETE DE RECHERCHES INDUSTRIELLES S.O.R.I. (FR) | 1984-10-10 | — | — | EP | claimed |
| EP-0069012-A1 | Benzoyl-phenyl-piperidine derivatives, their preparation and medicinal use | SOCIETE DE RECHERCHES INDUSTRIELLES S.O.R.I. (FR) | 1983-01-05 | — | — | EP | claimed |
| CN-112898233-B | Method for preparing amide compound by photocatalytic nitrogen-containing heterocyclic compound | 中南大学 | 2022-09-16 | — | — | CN | disclosed |
| CN-112898233-A | Method for preparing amide compound by photocatalytic nitrogen-containing heterocyclic compound | 中南大学 | 2021-06-04 | — | — | CN | disclosed |
| CN-100573323-C | The manufacture method of photosensitive paste and member for display panel | TORAY INDUSTRIES (JP) | 2009-12-23 | — | — | CN | disclosed |
| CN-1989454-A | Photosensitive paste and method for producing member for display panel | TORAY INDUSTRIES (JP) | 2007-06-27 | — | — | CN | disclosed |
| EP-0251832-A1 | Process for the preparation of benzoylphenyl piperidine derivatives | FOURNIER INNOVATION ET SYNERGIE (FR) | 1988-01-07 | — | — | EP | disclosed |
| EP-0251832-A1 | Process for the preparation of benzoylphenyl piperidine derivatives | FOURNIER INNOVATION ET SYNERGIE (FR) | 1988-01-07 | — | — | EP | disclosed |
| US-4680402-A | Benzoyl-phenyl-piperidine derivatives | SOCIETE DE RECHERCHES INDUSTRIELLES (S.O.R.I.) (FR) | 1987-07-14 | — | — | US | disclosed |
| US-4680402-A | Benzoyl-phenyl-piperidine derivatives | SOCIETE DE RECHERCHES INDUSTRIELLES (S.O.R.I.) (FR) | 1987-07-14 | — | — | US | disclosed |
| US-4528294-A | Benzoyl-phenyl-piperidine derivatives | SOCIETE DE RECHERCHES INDUSTRIELLE S.O.R.I. (FR) | 1985-07-09 | — | — | US | disclosed |
| US-4528294-A | Benzoyl-phenyl-piperidine derivatives | SOCIETE DE RECHERCHES INDUSTRIELLE S.O.R.I. (FR) | 1985-07-09 | — | — | US | disclosed |
| US-4528294-A | Benzoyl-phenyl-piperidine derivatives | SOCIETE DE RECHERCHES INDUSTRIELLE S.O.R.I. (FR) | 1985-07-09 | — | — | US | disclosed |
| EP-0069012-B1 | BENZOYL-PHENYL-PIPERIDINE DERIVATIVES, THEIR PREPARATION AND MEDICINAL USE | SOCIETE DE RECHERCHES INDUSTRIELLES S.O.R.I. (FR) | 1984-10-10 | — | — | EP | disclosed |
| EP-0069012-B1 | BENZOYL-PHENYL-PIPERIDINE DERIVATIVES, THEIR PREPARATION AND MEDICINAL USE | SOCIETE DE RECHERCHES INDUSTRIELLES S.O.R.I. (FR) | 1984-10-10 | — | — | EP | disclosed |
| EP-0069012-A1 | Benzoyl-phenyl-piperidine derivatives, their preparation and medicinal use | SOCIETE DE RECHERCHES INDUSTRIELLES S.O.R.I. (FR) | 1983-01-05 | — | — | EP | disclosed |
| EP-0069012-A1 | Benzoyl-phenyl-piperidine derivatives, their preparation and medicinal use | SOCIETE DE RECHERCHES INDUSTRIELLES S.O.R.I. (FR) | 1983-01-05 | — | — | EP | disclosed |
| EP-0069012-A1 | Benzoyl-phenyl-piperidine derivatives, their preparation and medicinal use | SOCIETE DE RECHERCHES INDUSTRIELLES S.O.R.I. (FR) | 1983-01-05 | — | — | EP | disclosed |