Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28538587 | 0.81 | ALDH1A1 (0.49) | ALDH1A1CYP1A2TSHRLMNATDP1 | |
| SCHEMBL17695124 | 0.81 | ALDH1A1 (0.49) | ALDH1A1CYP1A2TSHRLMNATDP1 | |
| SCHEMBL3325090 | 0.81 | ALDH1A1 (0.51) | ALDH1A1CYP1A2TSHRLMNATDP1 | |
| SCHEMBL3326982 | 0.79 | ALDH1A1 (0.49) | ALDH1A1CYP1A2TSHRTDP1HSD17B10 | |
| SCHEMBL8067996 | 0.78 | ALDH1A1 (0.59) | ALDH1A1CYP1A2TSHRLMNATDP1 | |
| SCHEMBL28398494 | 0.77 | ALDH1A1 (0.51) | ALDH1A1CYP1A2TSHRLMNATDP1 | |
| SCHEMBL3807727 | 0.76 | ALDH1A1 (0.46) | ALDH1A1CYP1A2TSHRLMNATDP1 | |
| SCHEMBL4620924 | 0.75 | ALDH1A1 (0.43) | ALDH1A1CYP1A2TSHRLMNATDP1 | |
| SCHEMBL7564168 | 0.75 | ALDH1A1 (0.49) | ALDH1A1CYP1A2TSHRLMNATDP1 | |
| SCHEMBL3035753 | 0.74 | ALDH1A1 (0.46) | ALDH1A1CYP1A2TSHRTDP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230192751-A1 | METHOD FOR THE PREPARATION OF OLIGONUCLEOTIDES | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIV (CA) | 2023-06-22 | — | — | US | claimed |
| EP-4179001-A2 | DEVICES AND METHODS FOR LIGHT-DIRECTED POLYMER SYNTHESIS | Twist Bioscience Corporation (US) | 2023-05-17 | — | — | EP | claimed |
| US-20220032256-A1 | DEVICES AND METHODS FOR LIGHT-DIRECTED POLYMER SYNTHESIS | Twist Bioscience Corporation | 2022-02-03 | — | — | US | claimed |
| WO-2022010934-A2 | DEVICES AND METHODS FOR LIGHT-DIRECTED POLYMER SYNTHESIS | Twist Bioscience Corporation (US) | 2022-01-13 | — | — | WO | claimed |
| EP-3720854-B1 | SOLID PHASE SYNTHESIS OF NIR FLUORESCENT PROBE | BRACCO IMAGING SPA (IT) | 2021-04-21 | — | — | EP | claimed |
| US-10822371-B2 | Solid phase synthesis of NIR fluorescent probe | BRACCO IMAGING S.P.A. (IT) | 2020-11-03 | — | — | US | claimed |
| EP-3720854-A1 | SOLID PHASE SYNTHESIS OF NIR FLUORESCENT PROBE | Bracco Imaging SpA (IT) | 2020-10-14 | — | — | EP | claimed |
| US-20200317722-A1 | SOLID PHASE SYNTHESIS OF NIR FLUORESCENT PROBE | BRACCO IMAGING S.P.A. (IT) | 2020-10-08 | — | — | US | claimed |
| WO-2019110639-A1 | SOLID PHASE SYNTHESIS OF NIR FLUORESCENT PROBE | BRACCO IMAGING SPA (IT) | 2019-06-13 | — | — | WO | claimed |
| EP-2334692-B1 | RNA MONOMERS CONTAINING O-ACETAL LEVULINYL ESTER GROUPS AND THEIR USE IN RNA MICROARRAYS | UNIV MCGILL (CA) | 2016-04-13 | — | — | EP | claimed |
| US-20230192751-A1 | METHOD FOR THE PREPARATION OF OLIGONUCLEOTIDES | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIV (CA) | 2023-06-22 | — | — | US | disclosed |
| EP-4179001-A2 | DEVICES AND METHODS FOR LIGHT-DIRECTED POLYMER SYNTHESIS | Twist Bioscience Corporation (US) | 2023-05-17 | — | — | EP | disclosed |
| US-20220032256-A1 | DEVICES AND METHODS FOR LIGHT-DIRECTED POLYMER SYNTHESIS | Twist Bioscience Corporation | 2022-02-03 | — | — | US | disclosed |
| WO-2022010934-A2 | DEVICES AND METHODS FOR LIGHT-DIRECTED POLYMER SYNTHESIS | Twist Bioscience Corporation (US) | 2022-01-13 | — | — | WO | disclosed |
| US-11041151-B2 | RNA array compositions and methods | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2021-06-22 | — | — | US | disclosed |
| EP-1431298-A1 | Mannitol and glucitol derivatives | Roche Diagnostics GmbH (DE) | 2004-06-23 | — | — | EP | disclosed |
| US-20030198982-A1 | Nucleic acid binding compounds containing pyrazolo[3,4-d]pyrimidine analogues of purin-2,6-diamine and their uses | ROCHE MOLECULAR SYSTEMS, INC. | 2003-10-23 | — | — | US | disclosed |
| EP-1307469-A1 | NUCLEIC ACID BINDING COMPOUNDS CONTAINING PYRAZOLO[3,4-D]PYRIMIDINE ANALOGUES OF PURIN-2,6-DIAMINE AND THEIR USES | BOEHRINGER MANNHEIM GMBH (DE) | 2003-05-07 | — | — | EP | disclosed |
| WO-2003035664-A2 | METHOD FOR COVALENTLY ATTACHING NUCLEOSIDES AND/OR NUCLEOTIDES ON SURFACES AND METHOD FOR DETERMINING COUPLING YIELDS IN THE SYNTHESIS OF NUCLEOTIDES | CHEMOGENIX GMBH (DE) | 2003-05-01 | — | — | WO | disclosed |
| WO-2002012263-A1 | NUCLEIC ACID BINDING COMPOUNDS CONTAINING PYRAZOLO[3,4-D]PYRIMIDINE ANALOGUES OF PURIN-2,6-DIAMINE AND THEIR USES | ROCHE DIAGNOSTICS GMBH (DE) | 2002-02-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200317722-A1 | SOLID PHASE SYNTHESIS OF NIR FLUORESCENT PROBE | MKI67, SSTR5, AURKA | ALDH1A1 3804/4885CYP1A2 2138/4885TSHR 1221/4885 |
| US-10822371-B2 | Solid phase synthesis of NIR fluorescent probe | MKI67, SSTR5, AURKA | ALDH1A1 3804/4885CYP1A2 2138/4885TSHR 1221/4885 |
| US-20030198982-A1 | Nucleic acid binding compounds containing pyrazolo[3,4-d]pyrimidine analogues of purin-2,6-diamine and their uses | ADAR, NT5C3B, NT5C2 | ALDH1A1 1810/4885CYP1A2 4394/4885TSHR 4040/4885 |
| US-20230192751-A1 | METHOD FOR THE PREPARATION OF OLIGONUCLEOTIDES | POLN, POLRMT, POLI | ALDH1A1 4284/4885CYP1A2 4863/4885TSHR 3504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.