Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | RELA | Q04206 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSH | P09668 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NFKBIA | P25963 | 2/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10698059 | 0.86 | MAPT (0.54) | MEN1KMT2ARELAALDH1A1CTSB | |
| SCHEMBL10622390 | 0.85 | RELA (0.52) | MEN1KMT2ARELAALDH1A1CTSB | |
| SCHEMBL20838491 | 0.74 | CTSB (0.49) | MEN1KMT2ARELAALDH1A1CTSB | |
| SCHEMBL2671539 | 0.74 | MEN1 (0.48) | MEN1KMT2AALDH1A1MAPTS1PR4 | |
| SCHEMBL30178231 | 0.73 | ALDH1A1 (0.49) | MEN1KMT2AALDH1A1MAPTNPC1 | |
| SCHEMBL10698487 | 0.73 | CTSB (0.48) | MEN1KMT2ARELAALDH1A1CTSB | |
| SCHEMBL13301370 | 0.73 | ALDH1A1 (0.49) | MEN1KMT2AALDH1A1MAPTNPC1 | |
| SCHEMBL6831160 | 0.72 | MAPT (0.55) | MEN1KMT2AALDH1A1MAPTHTT | |
| SCHEMBL12120523 | 0.71 | TXNRD1 (0.47) | MEN1KMT2AALDH1A1MAPTHTT | |
| SCHEMBL2474944 | 0.70 | HSP90AA1 (0.56) | MEN1KMT2ARELAALDH1A1CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0178775-B1 | FLUORESCENT INDICATOR DYES FOR CALCIUM IONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1988-11-09 | — | — | EP | disclosed |
| EP-0177202-B1 | CHELATORS WHOSE AFFINITY FOR CALCIUM IS DECREASED BY ILLUMINATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1988-05-25 | — | — | EP | disclosed |
| US-4689432-A | Chelators whose affinity for calcium is decreased by illumination | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1987-08-25 | — | — | US | disclosed |
| US-4603209-A | STILBENE-TYPE FLUOROPHORE, TWO AMINODIACETIC ACID MOIETIES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1986-07-29 | — | — | US | disclosed |
| EP-0178775-A2 | Fluorescent indicator dyes for calcium ions | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1986-04-23 | — | — | EP | disclosed |
| EP-0177202-A1 | Chelators whose affinity for calcium is decreased by illumination | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1986-04-09 | — | — | EP | disclosed |