Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 4/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | RBP4 | P02753 | 2/20 | 0.37 |
| ▸ | TTR | P02766 | 2/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11014645 | 0.77 | MGAM (0.45) | HDAC3HDAC1HDAC2ABL1MGAM | |
| SCHEMBL8727055 | 0.72 | HDAC3 (0.60) | HDAC3HDAC1HDAC2ABL1MGAM | |
| SCHEMBL15681572 | 0.72 | TERT (0.56) | HDAC3HDAC1HDAC2ABL1MGAM | |
| Hydrochloric Acid SCHEMBL15534244 | 0.71 | HDAC3 (0.59) | HDAC3HDAC1HDAC2ABL1MGAM | |
| SCHEMBL10922894 | 0.70 | MGAM (0.49) | HPGDSHDAC3HDAC1HDAC2MGAM | |
| SCHEMBL21835803 | 0.70 | CHEK1 (0.53) | HDAC3HDAC1HDAC2ABL1MGAM | |
| SCHEMBL10866344 | 0.69 | HDAC3 (0.41) | HPGDSHDAC3HDAC1HDAC2ABL1 | |
| SCHEMBL15666121 | 0.65 | CKS1B (0.48) | — | |
| SCHEMBL14155939 | 0.64 | USP2 (0.49) | HPGDSHDAC1 | |
| SCHEMBL4580665 | 0.64 | USP2 (0.49) | HPGDSHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0106489-B1 | ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1988-07-27 | — | — | EP | disclosed |