Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 3/20 | 0.53 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.53 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.53 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.52 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.52 |
| ▸ | ALPI | P09923 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | XIAP | P98170 | 1/20 | 0.50 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.50 |
| ▸ | AGXT | P21549 | 1/20 | 0.49 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | FCER2 | P06734 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL514507 | 1.00 | CYP2A6 (0.53) | CYP2A6ASIC3LOXL2S1PR4S1PR5 | |
| SCHEMBL4626056 | 1.00 | CYP2A6 (0.53) | CYP2A6ASIC3LOXL2S1PR4S1PR5 | |
| Trifluoroacetic Acid SCHEMBL6161390 | 0.92 | S1PR4 (0.46) | CYP2A6ASIC3LOXL2S1PR4S1PR5 | |
| SCHEMBL16461209 | 0.85 | CYP2A6 (0.58) | CYP2A6ASIC3LOXL2S1PR4S1PR5 | |
| SCHEMBL5323216 | 0.85 | CYP2A6 (0.50) | CYP2A6ASIC3LOXL2S1PR4S1PR5 | |
| SCHEMBL2032875 | 0.82 | CYP2A6 (0.50) | CYP2A6ASIC3LOXL2S1PR4S1PR5 | |
| SCHEMBL2030629 | 0.82 | CYP2A6 (0.50) | CYP2A6ASIC3LOXL2S1PR4S1PR5 | |
| SCHEMBL7026459 | 0.81 | AGXT (0.49) | CYP2A6ASIC3LOXL2AGXTBCL2L1 | |
| SCHEMBL26987594 | 0.79 | NNMT (0.54) | CYP2A6ASIC3LOXL2S1PR4S1PR5 | |
| SCHEMBL27130058 | 0.79 | NNMT (0.54) | CYP2A6ASIC3LOXL2S1PR4S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 158 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250059235-A1 | CYCLIC PEPTIDE ANTIVIRAL AGENTS AND METHODS USING SAME | UNIV DREXEL (US) | 2025-02-20 | — | — | US | claimed |
| CN-117529489-A | Bicyclic peptide ligands specific for NK cells | 拜斯科技术开发有限公司 | 2024-02-06 | — | — | CN | claimed |
| US-20230381327-A1 | REACTIVE CONJUGATES | DEBIOPHARM RESEARCH & MANUFACTURING S.A. (CH) | 2023-11-30 | — | — | US | claimed |
| US-20230355708-A1 | COMPOSITIONS FOR INHIBITING VIRAL ENTRY AND METHODS USING SAME | UNIV DREXEL (US) | 2023-11-09 | — | — | US | claimed |
| EP-4225378-A1 | REACTIVE CONJUGATES | Debiopharm Research & Manufacturing S.A. (CH) | 2023-08-16 | — | — | EP | claimed |
| US-20230046947-A1 | REACTIVE CONJUGATES | DEBIOPHARM RESEARCH & MANUFACTURING S.A. (CH) | 2023-02-16 | — | — | US | claimed |
| EP-4069311-A1 | REACTIVE CONJUGATES | Debiopharm Research & Manufacturing SA (CH) | 2022-10-12 | — | — | EP | claimed |
| US-20220204565-A1 | Cyclic Peptide Antiviral Agents and Methods Using Same | UNIV DREXEL (US) | 2022-06-30 | — | — | US | claimed |
| WO-2022079031-A1 | REACTIVE CONJUGATES | DEBIOPHARM RESEARCH & MANUFACTURING S.A. (CH) | 2022-04-21 | — | — | WO | claimed |
| WO-2022078566-A1 | REACTIVE CONJUGATES | DEBIOPHARM RESEARCH & MANUFACTURING S.A. (CH) | 2022-04-21 | — | — | WO | claimed |
| EP-0394853-A1 | Dipeptide-derivatives with enzym-inhibiting activity | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-10-31 | — | — | EP | claimed |
| EP-0394829-A1 | Renin-inhibiting dipeptides, process to synthetize them, compositions containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-10-31 | — | — | EP | claimed |
| EP-0373497-A2 | Dipeptide derivatives with an enzyme-inhibiting activity | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-06-20 | — | — | EP | claimed |
| EP-0372537-A2 | Urea derivatives of dipeptides with enzyme-inhibiting properties, process to make them, compositions containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-06-13 | — | — | EP | claimed |
| EP-0370383-A2 | Renin-inhibiting dipeptides, process to make them, compositions containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-05-30 | — | — | EP | claimed |
| EP-0333071-A2 | Polypeptides, methods for their preparation, pharmaceutical compositions comprising them and use | Eisai Co., Ltd. (JP) | 1989-09-20 | — | — | EP | claimed |
| EP-0329013-A2 | Renin-inhibiting amino acid derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-08-23 | — | — | EP | claimed |
| US-4855286-A | HYPOTENSIVE AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-08-08 | — | — | US | claimed |
| EP-0310015-A2 | Renin-inhibiting dipeptides, process for their preparation, medicines containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-04-05 | — | — | EP | claimed |
| EP-0255082-A2 | Renin-inhibiting di- and tripeptides, methods for their production, drugs containing them, and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-02-03 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220204565-A1 | Cyclic Peptide Antiviral Agents and Methods Using Same | ZC3HAV1, VIP, LNPEP | CYP2A6 4771/4885ASIC3 2611/4885LOXL2 4665/4885 |
| US-20230046947-A1 | REACTIVE CONJUGATES | FCGR3B, FCGR1A, FCGR2A | CYP2A6 2039/4885ASIC3 3664/4885LOXL2 3572/4885 |
| US-20250059235-A1 | CYCLIC PEPTIDE ANTIVIRAL AGENTS AND METHODS USING SAME | ZC3HAV1, VIP, LNPEP | CYP2A6 4771/4885ASIC3 2611/4885LOXL2 4665/4885 |
| US-20230355708-A1 | COMPOSITIONS FOR INHIBITING VIRAL ENTRY AND METHODS USING SAME | GALNT1, GALNT2, LGALS1 | CYP2A6 3819/4885ASIC3 3475/4885LOXL2 1887/4885 |
| US-20230381327-A1 | REACTIVE CONJUGATES | FCGR3B, FCGR1A, FCGR2A | CYP2A6 2050/4885ASIC3 3509/4885LOXL2 3658/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.