Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 6/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | PTGES | O14684 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PDE7B | Q9NP56 | 2/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8394979 | 0.78 | PDE7A (0.56) | PDE7AHTTMAPTPTGESGAA | |
| SCHEMBL10622791 | 0.78 | HPGD (0.47) | PDE7AHTTMAPTALDH1A1HPGD | |
| SCHEMBL9235115 | 0.77 | SIRT1 (0.47) | MAPTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL8866097 | 0.76 | PDE7A (0.68) | PDE7AMAPTPTGESGAAPDE7B | |
| SCHEMBL16216330 | 0.75 | AKR1C3 (0.52) | MAPTGAALMNAAKR1C3AKR1C2 | |
| SCHEMBL16207559 | 0.75 | AKR1C3 (0.52) | MAPTGAALMNAAKR1C3AKR1C2 | |
| SCHEMBL10914645 | 0.75 | AKR1C3 (0.52) | HTTMAPTGAALMNAAKR1C3 | |
| SCHEMBL5804176 | 0.75 | HSD17B10 (0.51) | MAPTGAASMN1; SMN2LMNAAKR1C3 | |
| SCHEMBL11180168 | 0.74 | TXNRD1 (0.54) | PDE7AHTTMAPTGAAPDE7B | |
| SCHEMBL6039967 | 0.74 | TXNRD1 (0.74) | PDE7AHTTMAPTGAAPDE7B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4771062-A | ENZYME INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 1988-09-13 | — | — | US | disclosed |