Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 14/20 | 0.56 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10618910 | 0.88 | PLA2G7 (0.71) | PLA2G7 | |
| SCHEMBL10731082 | 0.87 | PLA2G7 (0.54) | PLA2G7DAOLMNAGFERHPGD | |
| SCHEMBL10655643 | 0.86 | LMNA (0.60) | PLA2G7LMNA | |
| SCHEMBL11427587 | 0.86 | ALDH1A1 (0.52) | PLA2G7DAOLMNAGFERHPGD | |
| SCHEMBL10986003 | 0.78 | LMNA (0.58) | PLA2G7LMNA | |
| SCHEMBL10733027 | 0.78 | LMNA (0.58) | PLA2G7LMNA | |
| SCHEMBL10622902 | 0.78 | LMNA (0.76) | PLA2G7DAOLMNAGFERHPGD | |
| SCHEMBL7708557 | 0.76 | PLA2G7 (0.64) | PLA2G7LMNA | |
| SCHEMBL10735501 | 0.75 | PLA2G7 (0.66) | PLA2G7LMNA | |
| SCHEMBL10619100 | 0.75 | PLA2G7 (0.51) | PLA2G7DAOHRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0083186-B1 | THIAZOLE DERIVATIVES AS H2-RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1988-05-11 | — | — | EP | disclosed |
| US-4468399-A | ANTISECRETORY AGENTS, ANTIHISTAMINES | ELI LILLY AND COMPANY (US) | 1984-08-28 | — | — | US | disclosed |
| EP-0083186-A2 | Thiazole derivatives as H2-receptor antagonists | ELI LILLY AND COMPANY (US) | 1983-07-06 | — | — | EP | disclosed |
| EP-0003677-A2 | Pyrimidones, processes for their preparation and pharmaceutical compositions containing them | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1979-08-22 | — | — | EP | disclosed |