SCHEMBL10629564

SCHEMBL10629564

C=C(C)c1c2ccccc2c(C(=C)C)c2ccccc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.36
CYP1A2 P05177 1/20 0.36
POLB P06746 2/20 0.36
ALDH1A1 P00352 4/20 0.33
KDM4E B2RXH2 3/20 0.33
PAX8 Q06710 1/20 0.33
MAPK1 P28482 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MEN1 O00255 2/20 0.32
MAPT P10636 2/20 0.32
KMT2A Q03164 2/20 0.32
HPGD P15428 1/20 0.32
GAA P10253 1/20 0.32
ALOX15 P16050 1/20 0.32
CASP1 P29466 1/20 0.32
CASP7 P55210 1/20 0.32
GFER P55789 1/20 0.32
GPR3 P46089 1/20 0.32
HSD17B10 Q99714 2/20 0.32
CYP2A6 P11509 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13134232 0.81 PDE10A (0.47) CYP1A2POLBALDH1A1KDM4ESMN1; SMN2
SCHEMBL18905516 0.79 RAD52 (0.33) ALDH1A1KDM4EHPGDGAA
SCHEMBL18905422 0.78 KDM4E (0.34) IDO1CYP1A2ALDH1A1KDM4EMAPK1
SCHEMBL21955458 0.74 L3MBTL1 (0.36) IDO1CYP1A2POLBALDH1A1KDM4E
SCHEMBL23047287 0.74
SCHEMBL1506776 0.73 PTPN22 (0.52) IDO1CYP1A2POLBALDH1A1KDM4E
SCHEMBL1554945 0.73 ALDH1A1 (0.42) CYP1A2ALDH1A1MAPTHPGDGFER
SCHEMBL181822 0.71 THRB (0.52) POLBALDH1A1KDM4ESMN1; SMN2MEN1
SCHEMBL31146421 0.71 THRB (0.52) POLBALDH1A1KDM4ESMN1; SMN2MEN1
SCHEMBL107161 0.69 MEN1 (0.40) ALDH1A1KDM4EPAX8SMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4734824-A MONOOLEFIN OR DIOLEFIN HAVING THREE CONDENSED OR NONCONDENSED AROMATIC RINGS NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1988-03-29 US disclosed
EP-0154993-B1 ELECTRICAL INSULATING OIL AND ELECTRICAL APPLIANCES IMPREGNATED WITH THE SAME NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1988-03-09 EP disclosed
US-4621302-A MONO-OR DIOLEFIN HAVING THREE CONDENSED OR NON-CONDENSED AROMATIC RINGS NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1986-11-04 US disclosed
EP-0154993-A1 Electrical insulating oil and electrical appliances impregnated with the same NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1985-09-18 EP disclosed