SCHEMBL1554945

SCHEMBL1554945

C=C(C)c1ccc2ccccc2c1C(=C)C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.42
CYP2A6 P11509 2/20 0.42
TSHR P16473 2/20 0.42
HSD17B10 Q99714 2/20 0.42
TDP1 Q9NUW8 1/20 0.42
WDR5 P61964 1/20 0.41
LDHA P00338 1/20 0.40
HPRT1 P00492 1/20 0.39
NCEH1 Q6PIU2 1/20 0.38
PTK2B Q14289 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
MAPT P10636 1/20 0.38
HPGD P15428 1/20 0.38
PTPN22 Q9Y2R2 1/20 0.38
CYP1A2 P05177 1/20 0.38
CASP3 P42574 1/20 0.37
GFER P55789 1/20 0.37
SENP8 Q96LD8 1/20 0.37
SENP7 Q9BQF6 1/20 0.37
SENP6 Q9GZR1 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18539375 0.81 WDR5 (0.34) ALDH1A1CYP2A6TSHRHSD17B10TDP1
SCHEMBL11266839 0.80 TSHR (0.52) ALDH1A1CYP2A6TSHRHSD17B10TDP1
SCHEMBL13273691 0.80 LDHA (0.58) LDHAMAPTPTPN22CYP1A2HIF1A
SCHEMBL1506776 0.80 PTPN22 (0.52) ALDH1A1CYP2A6TSHRHSD17B10TDP1
SCHEMBL273123 0.77 PTK2B (0.55) ALDH1A1CYP2A6TSHRHSD17B10TDP1
SCHEMBL29563474 0.77 PTK2B (0.55) ALDH1A1CYP2A6TSHRHSD17B10TDP1
SCHEMBL25067043 0.76 MEN1 (0.40) ALDH1A1HSD17B10LDHAPTK2BL3MBTL1
SCHEMBL8609970 0.76 NCEH1 (0.44) ALDH1A1CYP2A6TSHRHSD17B10TDP1
SCHEMBL5039147 0.76 NCEH1 (0.44) ALDH1A1CYP2A6TSHRHSD17B10TDP1
SCHEMBL9572195 0.76 ALDH1A1 (0.38) ALDH1A1CYP2A6TSHRHSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240287009-A1 AMINE-FUNCTIONAL MONOMERS AND METHODS OF MAKING SAME INFINEUM INTERNATIONAL LIMITED (GB) 2024-08-29 US claimed
EP-4410772-A2 AMINE-FUNCTIONAL MONOMERS AND METHODS OF MAKING SAME Infineum International Limited (GB) 2024-08-07 EP claimed
CN-118440229-A Amine functional monomers and methods of making the same 英菲诺姆国际有限公司 2024-08-06 CN claimed
CN-116410594-B Resin composition, prepreg and metal foil-clad laminate 广东生益科技股份有限公司 2024-06-14 CN claimed
CN-116410594-A Resin composition, prepreg and metal foil-clad laminate 广东生益科技股份有限公司 2023-07-11 CN claimed
CN-116410584-A Prepreg, laminated board, metal-clad foil plate and application thereof 广东生益科技股份有限公司 2023-07-11 CN claimed
US-5597876-A CURING AGENT PROVIDES BETTER MECHANICAL PROPERTIES AT HIGH TEMPERATURE SHELL OIL COMPANY (US) 1997-01-28 US claimed
EP-0088223-B1 MANUFACTURE OF ISOCYANATES AMERICAN CYANAMID COMPANY (US) 1985-04-17 EP claimed
EP-0088223-A1 Manufacture of isocyanates AMERICAN CYANAMID COMPANY (US) 1983-09-14 EP claimed
US-4379767-A Manufacture of isocyanates AMERICAN CYANAMID COMPANY (US) 1983-04-12 US claimed
CN-118255939-B Benzocyclobutene resin, resin composition containing benzocyclobutene resin and application of benzocyclobutene resin 广东生益科技股份有限公司 2025-06-03 CN disclosed
CN-116285378-B Resin composition, adhesive sheet containing same, and metal foil-clad laminate 广东生益科技股份有限公司 2025-05-16 CN disclosed
CN-119490631-A Thermosetting resin composition, resin adhesive film and application thereof 广东生益科技股份有限公司 2025-02-21 CN disclosed
CN-119490723-A Resin composition, resin film containing resin composition and printed circuit board 广东生益科技股份有限公司 2025-02-21 CN disclosed
US-20240287009-A1 AMINE-FUNCTIONAL MONOMERS AND METHODS OF MAKING SAME INFINEUM INTERNATIONAL LIMITED (GB) 2024-08-29 US disclosed
EP-0088218-A1 Preparation of tertiary alkyl isocyanates AMERICAN CYANAMID COMPANY (US) 1983-09-14 EP disclosed
US-4399074-A FROM THE HALIDE, CATALYST COMPLEX OF ZINC SALT, PYRIDINE AND ALKALI METAL CYANATE AMERICAN CYANAMID COMPANY (US) 1983-08-16 US disclosed
US-4399073-A FROM THE HALIDE AND ALKALI METAL CYANATE, WATER AMERICAN CYANAMID COMPANY (US) 1983-08-16 US disclosed
US-4039593-A CAPPING ORGANO-DILITHIUM POLYMERS, N,N,N*,N*-TETRAMETHYLENEDIAMINE ON LITHIUM CORPORATION OF AMERICA (US) 1977-08-02 US disclosed
US-3954894-A Organotrilithium polymerization initiators LITHIUM CORPORATION OF AMERICA (US) 1976-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240287009-A1 AMINE-FUNCTIONAL MONOMERS AND METHODS OF MAKING SAME AMD1, HNMT, MAT1A ALDH1A1 317/4885CYP2A6 4391/4885TSHR 4397/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.