SCHEMBL181822

SCHEMBL181822

CC(=O)c1c2ccccc2c(C(C)=O)c2ccccc12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.52
CA12 O43570 2/20 0.48
CA9 Q16790 2/20 0.48
TP53 P04637 1/20 0.48
HSD17B10 Q99714 1/20 0.48
EGFR P00533 1/20 0.48
SRC P12931 1/20 0.48
KDM4E B2RXH2 2/20 0.47
ALDH1A1 P00352 2/20 0.47
POLB P06746 3/20 0.46
MAPT P10636 3/20 0.45
PBRM1 Q86U86 1/20 0.45
MEN1 O00255 1/20 0.45
NSD2 O96028 1/20 0.45
KMT2A Q03164 1/20 0.45
MCL1 Q07820 1/20 0.45
GAA P10253 1/20 0.44
HPGD P15428 1/20 0.43
HTT P42858 1/20 0.43
NCEH1 Q6PIU2 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31146421 1.00 THRB (0.52) THRBCA12CA9TP53HSD17B10
SCHEMBL1666371 0.92 THRB (0.50) THRBCA12CA9TP53HSD17B10
SCHEMBL1040657 0.90 HSD17B10 (0.47) THRBCA12CA9TP53HSD17B10
SCHEMBL29491183 0.83 ALDH1A1 (0.65) THRBCA12CA9TP53HSD17B10
SCHEMBL30881957 0.83 TP53 (0.46) THRBCA12CA9TP53HSD17B10
SCHEMBL67303 0.83 ALDH1A1 (0.65) THRBCA12CA9TP53HSD17B10
SCHEMBL11772265 0.83 ALDH1A1 (0.58) THRBCA12CA9TP53HSD17B10
SCHEMBL1042811 0.82 PLK1 (0.40) THRBCA12CA9TP53HSD17B10
SCHEMBL12220557 0.81 HSD17B10 (0.62) TP53HSD17B10KDM4EALDH1A1POLB
SCHEMBL1669173 0.81 TP53 (0.44) THRBCA12CA9TP53HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 363 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9716235-B2 9,10-bis[2-(p-substituted phenyl)pyrimidin-4-yl] anthracene compounds, methods of preparing the same, organic electroluminescent devices and organic electroluminescent display apparatus BOE TECHNOLOGY GROUP CO., LTD. (CN) 2017-07-25 US claimed
US-20150214487-A1 9,10-Bis[2-(p-substituted phenyl)pyrimidin-4-yl] Anthracene Compounds, Methods of Preparing the Same, Organic Electroluminescent Devices and Organic Electroluminescent Display Apparatus BOE TECHNOLOGY GROUP CO., LTD. (CN) 2015-07-30 US claimed
CN-103382181-B Multiaryl-substituted pyrimidine derivative, its preparation method, organic electroluminescent device, and organic electroluminescent display device BOE TECHNOLOGY GROUP CO LTD 2015-05-20 CN claimed
CN-103382181-A Multiaryl-substituted pyrimidine derivative, its preparation method, organic electroluminescent device, and organic electroluminescent display device BOE TECHNOLOGY GROUP CO LTD 2013-11-06 CN claimed
US-12102499-B2 Two-part dental sealant, method of applying with a syringe device, and kit SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2024-10-01 US disclosed
WO-2024121658-A1 SURFACE-TREATED FILLER, DENTAL COMPOSITION CONTAINING SUCH A FILLER, PROCESS OF PRODUCTION AND USE THEREOF SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2024-06-13 WO disclosed
CN-118054082-A Nonaqueous electrolyte additive, nonaqueous electrolyte containing same and secondary battery 蜂巢能源科技股份有限公司 2024-05-17 CN disclosed
WO-2023209463-A1 DENTAL COMPOSITION CONTAINING A RESORCINOL OR CATECHOL MOIETY CONTAINING COMPONENT AND USE THEREOF 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-11-02 WO disclosed
EP-4035647-B1 TWO-COMPONENT SELF-ADHESIVE DENTAL COMPOSITION, PROCESS OF PRODUCTION AND USE THEREOF 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-10-18 EP disclosed
EP-3043766-B1 DENTAL COMPOSITION CONTAINING POLYOXOMETALATES, PROCESS OF PRODUCTION AND USE THEREOF 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-07-19 EP disclosed
US-20230134622-A1 TWO-PART DENTAL SEALANT, METHOD OF APPLYING WITH A SYRINGE DEVICE, AND KIT SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2023-05-04 US disclosed
US-20230051188-A1 COMPOSITION INCLUDING UNSATURATED POLYESTER RESIN, EPOXY RESIN, AND PHOTOINITIATOR AND METHOD OF USING THE SAME 3M INNOVATIVE PROPERTIES COMPANY 2023-02-16 US disclosed
EP-0369645-A1 Triazine photoinitiators in a ternary system for addition polymerization MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-05-23 EP disclosed
US-4921923-A Ethers of oligomeric phenol-diketone condensation products and a vinyl-benzyl compound ALLIED SIGNAL INC. (US) 1990-05-01 US disclosed
US-4828583-A MIXTUE OF ARYLIDONIUM SALT, SENSITIZER AND ELECTRON DONOR MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-05-09 US disclosed
US-4792506-A FREE RADICAL POLYMERIZATION OF VINYL MONOMERS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-12-20 US disclosed
EP-0290133-A2 Ternary photoinitiator system for addition polymerization MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-11-09 EP disclosed
EP-0285369-A2 Coated abrasive binder containing ternary photoinitiator system MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-10-05 EP disclosed
US-4735632-A RAPID AND DEEP CURE OF BINDER OF MONOMER, ARYLIDONIUM SALT, SENSITIZER, AND ELECTRON DONOR MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-04-05 US disclosed
EP-0260877-A2 Photosensitizers and polymerizable compositions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-03-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230134622-A1 TWO-PART DENTAL SEALANT, METHOD OF APPLYING WITH A SYRINGE DEVICE, AND KIT MMAB, SRM, MAT2A THRB 3120/4885CA12 3756/4885CA9 2990/4885
US-12102499-B2 Two-part dental sealant, method of applying with a syringe device, and kit MMAB, SRM, MAT2A THRB 3120/4885CA12 3756/4885CA9 2990/4885
US-20150214487-A1 9,10-Bis[2-(p-substituted phenyl)pyrimidin-4-yl] Anthracene Compounds, Methods of Preparing the Same, Organic Electroluminescent Devices and Organic Electroluminescent Display Apparatus P2RY10, P2RY4, APRT THRB 4028/4885CA12 4268/4885CA9 1127/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.