Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 1/20 | 0.62 |
| ▸ | MMP8 | P22894 | 1/20 | 0.62 |
| ▸ | MMP13 | P45452 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ACACB | O00763 | 6/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | PLK1 | P53350 | 1/20 | 0.47 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.47 |
| ▸ | ACACA | Q13085 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11081564 | 0.85 | MMP9 (0.56) | MMP9MMP8MMP13LMNAGAA | |
| SCHEMBL28594599 | 0.83 | TAS1R3 (0.51) | LMNAACACBPLK1GPR88ACACA | |
| SCHEMBL28140713 | 0.81 | AKR1C3 (0.54) | MMP9MMP8MMP13CA1CA2 | |
| SCHEMBL11080561 | 0.79 | MMP9 (0.64) | MMP9MMP8MMP13LMNAGAA | |
| SCHEMBL6325271 | 0.79 | LMNA (0.68) | MMP9MMP8MMP13LMNAGAA | |
| SCHEMBL11278038 | 0.77 | LMNA (0.58) | MMP9MMP8MMP13LMNAGAA | |
| SCHEMBL31437697 | 0.77 | GAA (0.62) | MMP9MMP8MMP13LMNAGAA | |
| SCHEMBL5213990 | 0.76 | MAPK1 (0.57) | MMP9MMP8MMP13LMNAL3MBTL1 | |
| SCHEMBL4943215 | 0.75 | LMNA (0.54) | MMP9MMP8MMP13LMNATDP1 | |
| SCHEMBL28234925 | 0.75 | CRHBP (0.53) | MMP9MMP8MMP13LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007124136-A1 | USE OF 4-AMINO-PIPERIDINES FOR TREATING SLEEP DISORDERS | ACADIA PHARMACEUTICALS, INC. (US) | 2007-11-01 | — | — | WO | disclosed |