Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MC4R | P32245 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | MC3R | P41968 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.44 |
| ▸ | CCNC | P24863 | 1/20 | 0.42 |
| ▸ | CDK8 | P49336 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29643294 | 1.00 | ALDH1A1 (0.54) | ALDH1A1MAPTL3MBTL1KDM4CLMNA | |
| Hydrochloric Acid SCHEMBL27262522 | 0.98 | ALDH1A1 (0.53) | ALDH1A1MAPTL3MBTL1KDM4CLMNA | |
| Trifluoroacetic Acid SCHEMBL16318459 | 0.88 | L3MBTL1 (0.46) | ALDH1A1MAPTL3MBTL1KDM4CLMNA | |
| SCHEMBL27715023 | 0.83 | ALDH1A1 (0.58) | ALDH1A1MAPTL3MBTL1KDM4CRAB9A | |
| SCHEMBL27513588 | 0.82 | GRM4 (0.49) | ALDH1A1MAPTL3MBTL1LMNATSHR | |
| SCHEMBL177940 | 0.81 | ALDH1A1 (0.56) | ALDH1A1MAPTL3MBTL1KDM4CRAB9A | |
| SCHEMBL31151693 | 0.81 | ALDH1A1 (0.61) | ALDH1A1MAPTL3MBTL1KDM4CLMNA | |
| SCHEMBL202448 | 0.81 | ALDH1A1 (0.61) | ALDH1A1MAPTL3MBTL1KDM4CLMNA | |
| SCHEMBL31607215 | 0.81 | ALDH1A1 (0.56) | ALDH1A1MAPTL3MBTL1KDM4CRAB9A | |
| SCHEMBL27817832 | 0.80 | ALDH1A1 (0.47) | ALDH1A1MAPTL3MBTL1KDM4CLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 579 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113061098-B | Amide compound and derivative thereof, preparation method, pharmaceutical composition and application | 中国药科大学 | 2022-08-30 | — | — | CN | claimed |
| WO-2022057164-A1 | PREPARATION METHOD FOR MULTI-TARGET ANTI-TUMOR DRUG | 广州南鑫药业有限公司 | 2022-03-24 | — | — | WO | claimed |
| CN-112159351-B | Preparation method of multi-target antitumor drug | 广州南鑫药业有限公司 | 2021-12-07 | — | — | CN | claimed |
| CN-112679424-A | Synthesis method of regorafenib | 苏州特瑞药业有限公司 | 2021-04-20 | — | — | CN | claimed |
| CN-112279809-A | Preparation method of 2-cyano-4-fluoropyridine | 山东省海洋化工科学研究院 | 2021-01-29 | — | — | CN | claimed |
| CN-112159351-A | Preparation method of multi-target antitumor drug | 广州南鑫药业有限公司 | 2021-01-01 | — | — | CN | claimed |
| CN-108752270-A | A kind of 4- bromo-2-pyridyl amides compounds of the ether structure containing hexichol | 湖南博隽生物医药有限公司 | 2018-11-06 | — | — | CN | claimed |
| CN-108440402-A | A kind of preparation method of 2- amino -4- fluorine pyridines | 上海凌凯医药科技有限公司 | 2018-08-24 | — | — | CN | claimed |
| CN-106543077-A | N, N ' disubstituted arylthiourea derivative and its synthetic method and application | 西安交通大学 | 2017-03-29 | — | — | CN | claimed |
| EP-2244706-B1 | GLUCOKINASE ACTIVATORS | MERCK PATENT GMBH (DE) | 2016-04-06 | — | — | EP | claimed |
| CN-102791693-A | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2012-11-21 | — | — | CN | claimed |
| US-20110312935-A1 | 1H-Benz Imidazole-5-Carboxamides As Anti-Inflammatory Agents | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-12-22 | — | — | US | claimed |
| CN-101959515-A | Glucokinase activators | MERCK PATENT GMBH | 2011-01-26 | — | — | CN | claimed |
| EP-2244706-A1 | GLUCOKINASE ACTIVATORS | Merck Patent GmbH (DE) | 2010-11-03 | — | — | EP | claimed |
| WO-2010034796-A1 | 1H-BENZ IMIDAZOLE-5-CARBOXAMIDES AS ANTI-INFLAMMATORY AGENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-01 | — | — | WO | claimed |
| WO-2009106203-A1 | GLUCOKINASE ACTIVATORS | MERCK PATENT GMBH (DE) | 2009-09-03 | — | — | WO | claimed |
| US-12612399-B2 | Substituted 4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)thiophene-2-carboxamide derivatives and use thereof | THE JOHNS HOPKINS UNIVERSITY (US) | 2026-04-28 | — | — | US | disclosed |
| CN-119241427-A | Method for comprehensively and efficiently synthesizing anticancer drug regorafenib | 董帅圻 | 2025-01-03 | — | — | CN | disclosed |
| US-4097489-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1978-06-27 | — | — | US | disclosed |
| US-4069224-A | N-(PYRIDYLALKYL)BENZAMIDES, IMPROVE PRODUCTION OF PROSTAGLANDINS IN MAMMALS | THE UPJOHN COMPANY (US) | 1978-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110312935-A1 | 1H-Benz Imidazole-5-Carboxamides As Anti-Inflammatory Agents | MAPRE2, MAPRE1, H1-4 | ALDH1A1 1202/4885MAPT 480/4885L3MBTL1 716/4885 |
| US-12612399-B2 | Substituted 4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)thiophene-2-carboxamide derivatives and use thereof | SNCA, CBR1, CBR3 | ALDH1A1 1182/4885MAPT 449/4885L3MBTL1 725/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.