Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10646620 | 0.86 | SIGMAR1 (0.54) | MEN1KMT2ASIGMAR1KDM4EALDH1A1 | |
| SCHEMBL10668329 | 0.82 | BRD4 (0.45) | AVPR1AKDM4EALDH1A1BRD4GAA | |
| SCHEMBL10671837 | 0.80 | BRD4 (0.46) | MEN1KMT2AAVPR1AALDH1A1BRD4 | |
| SCHEMBL10671525 | 0.79 | SMN1; SMN2 (0.47) | MEN1KMT2ASIGMAR1AVPR1AKDM4E | |
| SCHEMBL10649474 | 0.79 | ALDH1A1 (0.47) | MEN1KMT2AAVPR1AALDH1A1BRD4 | |
| SCHEMBL10648058 | 0.79 | MC4R (0.59) | MEN1KMT2ASIGMAR1AVPR1AALDH1A1 | |
| SCHEMBL10650122 | 0.77 | KDM4E (0.50) | MEN1KMT2AAVPR1AKDM4EALDH1A1 | |
| SCHEMBL10671068 | 0.77 | HRH3 (0.44) | AVPR1AALDH1A1BRD4FAAH | |
| SCHEMBL10651709 | 0.75 | LMNA (0.44) | AVPR1AKDM4EALDH1A1LMNA | |
| SCHEMBL9685664 | 0.73 | HRH2 (0.57) | MEN1KMT2AATMSIGMAR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0261804-A1 | Dopamine-beta-hydroxylase inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 1988-03-30 | — | — | EP | disclosed |