Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | MC4R | P32245 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HBB | P68871 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CHKA | P35790 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10671837 | 0.87 | BRD4 (0.46) | BRD4AVPR1AMC4RGBA1ALDH1A1 | |
| SCHEMBL10649474 | 0.86 | ALDH1A1 (0.47) | BRD4AVPR1AMC4RDRD2DRD3 | |
| SCHEMBL10671525 | 0.86 | SMN1; SMN2 (0.47) | BRD4AVPR1AMC4RALDH1A1KDM4E | |
| SCHEMBL10648058 | 0.85 | MC4R (0.59) | AVPR1AMC4RALDH1A1ALOX15HSD17B10 | |
| SCHEMBL10646620 | 0.84 | SIGMAR1 (0.54) | ALDH1A1HSD17B10KDM4EGAA | |
| SCHEMBL10650122 | 0.83 | KDM4E (0.50) | BRD4AVPR1ADRD2DRD3ALDH1A1 | |
| SCHEMBL10671068 | 0.83 | HRH3 (0.44) | BRD4AVPR1AMC4RDRD2DRD3 | |
| SCHEMBL10648303 | 0.82 | MEN1 (0.40) | BRD4AVPR1AALDH1A1KDM4EGAA | |
| SCHEMBL10651709 | 0.81 | LMNA (0.44) | AVPR1AMC4RALDH1A1HRH4HRH3 | |
| SCHEMBL10370696 | 0.80 | MC4R (0.62) | BCL2L1MC4RDRD2DRD3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4761415-A | HYPOTENSIVE | SMITHKLINE BECKMAN CORPORATION (US) | 1988-08-02 | — | — | US | disclosed |