SCHEMBL10651284

SCHEMBL10651284

CC(C)(C)CSc1ccc(S)cc1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL508028 0.79 HPGD (0.44) ALDH1A1SMN1; SMN2
SCHEMBL10644798 0.77 MAOA (0.43) ALDH1A1SMN1; SMN2
SCHEMBL23099811 0.77 CYP3A4 (0.44) ALDH1A1
SCHEMBL10080198 0.76 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2
SCHEMBL8372191 0.73 SLC6A4 (0.47) ALDH1A1
SCHEMBL13918974 0.73 MEN1 (0.44) ALDH1A1
SCHEMBL19261552 0.72 APP (0.43) ALDH1A1SMN1; SMN2
SCHEMBL6486405 0.71 HTT (0.50) ALDH1A1SMN1; SMN2
SCHEMBL25384705 0.70 CA2 (0.45) ALDH1A1SMN1; SMN2
SCHEMBL23092434 0.70 MAPT (0.47) ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0273242-A2 2-Pyri(mi)dylthio-aryl ether BAYER AG (DE) 1988-07-06 EP disclosed