SCHEMBL25384705

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3494898	0.79	CA2 (0.47)	CA2LMNAALDH1A1TSHRNT5E
	SCHEMBL28772561	0.75	LMNA (0.46)	CA2LMNAALDH1A1TSHRNT5E
	SCHEMBL6486405	0.72	HTT (0.50)	CA2ALDH1A1TSHRCA1CA12
	SCHEMBL7998600	0.72	CA2 (0.49)	CA2LMNAALDH1A1TSHRNT5E
	SCHEMBL1892147	0.71	TSHR (0.55)	LMNAALDH1A1TSHRNT5ESMN1; SMN2
	SCHEMBL11100709	0.71	ESR1 (0.54)	CA2LMNAALDH1A1TSHRNT5E
	SCHEMBL25385935	0.71	ALDH1A1 (0.53)	CA2LMNAALDH1A1TSHRNT5E
	SCHEMBL518141	0.71	LMNA (0.56)	CA2LMNAALDH1A1TSHRNT5E
	SCHEMBL979380	0.71	LMNA (0.56)	CA2LMNAALDH1A1TSHRNT5E
	SCHEMBL565078	0.71	LMNA (0.56)	CA2LMNAALDH1A1TSHRNT5E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.