Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10652711 | 0.83 | MEN1 (0.52) | ALDH1A1NR4A1MEN1NPC1RAB9A | |
| SCHEMBL10655575 | 0.83 | TDP1 (0.44) | ALDH1A1MEN1KMT2APOLBHSPB1 | |
| SCHEMBL10652647 | 0.80 | CA12 (0.47) | ALDH1A1NR4A1MEN1RAB9AKMT2A | |
| SCHEMBL11089561 | 0.76 | GPR17 (0.43) | ALDH1A1NR4A1CA12CA1CA2 | |
| SCHEMBL544826 | 0.75 | HTR6 (0.44) | ALDH1A1NR4A1MEN1NPC1RAB9A | |
| SCHEMBL10656325 | 0.74 | SOS1 (0.46) | ALDH1A1NR4A1MEN1RAB9AKMT2A | |
| SCHEMBL11846316 | 0.74 | F2 (0.44) | NR4A1MEN1KMT2A | |
| SCHEMBL11841711 | 0.73 | ALPL (0.51) | ALDH1A1NR4A1CA1CA2CA9 | |
| SCHEMBL11846331 | 0.73 | LMNA (0.56) | ALDH1A1NR4A1MEN1KMT2ACA1 | |
| SCHEMBL11842624 | 0.72 | F2 (0.46) | ALDH1A1NR4A1MEN1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0115039-B1 | SUBSTITUTED PHENYLSULFONYLOXYBENZIMIDAZOLE CARBAMATES, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION AS MEDICAMENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-02-10 | — | — | EP | disclosed |
| US-4639463-A | Substituted phenylsulfonyloxybenzimidazolecarbamates and anthelmintic compositions | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-01-27 | — | — | US | disclosed |
| EP-0115039-A1 | Substituted phenylsulfonyloxybenzimidazole carbamates, process for their preparation and their application as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-08-08 | — | — | EP | disclosed |