Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10653486 | 0.89 | KMT2A (0.49) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL3601604 | 0.85 | CYP1A2 (0.58) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL1500911 | 0.84 | MEN1 (0.46) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL10653936 | 0.84 | MAPT (0.49) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL10651996 | 0.83 | SIGMAR1 (0.43) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL10650486 | 0.83 | MAPT (0.53) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL10651304 | 0.81 | ALDH1A1 (0.46) | MEN1KMT2AMAPTTDP1LMNA | |
| SCHEMBL9726177 | 0.80 | CYP1A2 (0.50) | MEN1KMT2ANPC1RAB9ALMNA | |
| SCHEMBL9726173 | 0.80 | CYP1A2 (0.50) | MEN1KMT2ANPC1RAB9ALMNA | |
| SCHEMBL10652092 | 0.80 | POLB (0.41) | MEN1KMT2ANPC1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4755509-A | Heterocyclic aldose reductase inhibitors and methods of using them | Carbipem (FR) | 1988-07-05 | — | — | US | disclosed |