Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | EDNRA | P25101 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10654625 | 0.93 | MEN1 (0.42) | KDM4EMAPTHTTMEN1KMT2A | |
| SCHEMBL10655064 | 0.90 | ALDH1A1 (0.35) | KDM4EMAPTHTTMEN1KMT2A | |
| SCHEMBL10654499 | 0.80 | RECQL (0.36) | KDM4EMAPTHTTMEN1KMT2A | |
| SCHEMBL10654033 | 0.78 | KDM4E (0.51) | KDM4EMAPTHTTMEN1KMT2A | |
| SCHEMBL10652373 | 0.76 | KDM4E (0.40) | KDM4EMAPTHTTMEN1KMT2A | |
| SCHEMBL10652350 | 0.76 | KDM4E (0.56) | KDM4EMAPTHTTMEN1KMT2A | |
| SCHEMBL10655257 | 0.74 | KDM4E (0.51) | KDM4EMAPTHTTMEN1KMT2A | |
| SCHEMBL10655975 | 0.72 | KDM4E (0.45) | KDM4EMAPTHTTMEN1KMT2A | |
| SCHEMBL10652305 | 0.71 | KDM4E (0.41) | KDM4EMAPTHTTMEN1KMT2A | |
| SCHEMBL10654988 | 0.70 | MEN1 (0.52) | KDM4EMAPTHTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0092380-B1 | ANTIALLERGIC 4H-FURO(3,2-B)INDOLES AND THEIR PRODUCTION | WARNER-LAMBERT COMPANY (US) | 1988-01-20 | — | — | EP | claimed |
| EP-0092380-A2 | Antiallergic 4H-furo(3,2-b)indoles and their production | WARNER-LAMBERT COMPANY (US) | 1983-10-26 | — | — | EP | claimed |