Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10655064 | 0.90 | ALDH1A1 (0.35) | RECQLALDH1A1TSHRHTTMAPT | |
| SCHEMBL10654625 | 0.89 | MEN1 (0.42) | ALDH1A1TSHRHTTSMN1; SMN2MAPT | |
| SCHEMBL10653000 | 0.80 | KDM4E (0.45) | ALDH1A1TSHRHTTSMN1; SMN2MAPT | |
| SCHEMBL10654412 | 0.77 | RECQL (0.41) | RECQLALDH1A1TSHRHTTSMN1; SMN2 | |
| SCHEMBL10652379 | 0.75 | PPARG (0.33) | RECQLALDH1A1TSHRSMN1; SMN2MAPT | |
| SCHEMBL10654421 | 0.75 | ALDH1A1 (0.44) | RECQLALDH1A1TSHRSMN1; SMN2MAPT | |
| SCHEMBL10652918 | 0.72 | MAPK8 (0.43) | RECQLALDH1A1HTTSMN1; SMN2MAPT | |
| SCHEMBL10654396 | 0.71 | ALDH1A1 (0.38) | RECQLALDH1A1TSHRHTTSMN1; SMN2 | |
| SCHEMBL10654464 | 0.70 | RECQL (0.35) | RECQLALDH1A1TSHRHTTSMN1; SMN2 | |
| SCHEMBL10654374 | 0.67 | LMNA (0.42) | RECQLALDH1A1TSHRHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0092380-B1 | ANTIALLERGIC 4H-FURO(3,2-B)INDOLES AND THEIR PRODUCTION | WARNER-LAMBERT COMPANY (US) | 1988-01-20 | — | — | EP | claimed |
| EP-0092380-A2 | Antiallergic 4H-furo(3,2-b)indoles and their production | WARNER-LAMBERT COMPANY (US) | 1983-10-26 | — | — | EP | claimed |