Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | REN | P00797 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10653000 | 0.90 | KDM4E (0.45) | ALDH1A1TSHRMEN1KMT2AHSD17B10 | |
| SCHEMBL10654499 | 0.90 | RECQL (0.36) | ALDH1A1TSHRMEN1KMT2AHSD17B10 | |
| SCHEMBL10654625 | 0.83 | MEN1 (0.42) | ALDH1A1TSHRMEN1KMT2AHSD17B10 | |
| SCHEMBL10654374 | 0.76 | LMNA (0.42) | ALDH1A1TSHRPKMMEN1KMT2A | |
| SCHEMBL10652614 | 0.74 | LMNA (0.41) | ALDH1A1TSHRPKMMEN1KMT2A | |
| SCHEMBL10653794 | 0.73 | LMNA (0.43) | ALDH1A1TSHRPKMMEN1KMT2A | |
| SCHEMBL10654460 | 0.71 | NR4A2 (0.43) | ALDH1A1TSHRPKMMEN1KMT2A | |
| SCHEMBL10654484 | 0.69 | LMNA (0.41) | ALDH1A1TSHRPKMMEN1KMT2A | |
| SCHEMBL10655883 | 0.68 | PKM (0.34) | ALDH1A1TSHRPKMMEN1KMT2A | |
| SCHEMBL10654412 | 0.67 | RECQL (0.41) | ALDH1A1TSHRMEN1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0092380-B1 | ANTIALLERGIC 4H-FURO(3,2-B)INDOLES AND THEIR PRODUCTION | WARNER-LAMBERT COMPANY (US) | 1988-01-20 | — | — | EP | claimed |
| EP-0092380-A2 | Antiallergic 4H-furo(3,2-b)indoles and their production | WARNER-LAMBERT COMPANY (US) | 1983-10-26 | — | — | EP | claimed |