Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 15/20 | 0.64 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 10/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 10/20 | 0.42 |
| ▸ | BCHE | P06276 | 9/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10654771 | 0.83 | ACHE (0.63) | ACHEGRIN1GRIN2ABCHEKDM4E | |
| SCHEMBL10651092 | 0.80 | ACHE (0.62) | ACHEGRIN1GRIN2ABCHE | |
| SCHEMBL9039832 | 0.79 | ACHE (1.00) | ACHEGRIN1GRIN2ABCHEKDM4E | |
| SCHEMBL10653196 | 0.75 | ACHE (0.70) | ACHEDCPSGRIN1GRIN2ABCHE | |
| SCHEMBL28984974 | 0.75 | ACHE (0.66) | ACHEDCPSGRIN1GRIN2ABCHE | |
| SCHEMBL9209834 | 0.75 | ACHE (0.59) | ACHEGRIN1GRIN2ABCHEKDM4E | |
| SCHEMBL10653208 | 0.74 | ACHE (0.58) | ACHEGRIN1GRIN2ABCHEKDM4E | |
| SCHEMBL9172013 | 0.73 | ACHE (0.66) | ACHEGRIN1GRIN2ABCHEKDM4E | |
| SCHEMBL9208760 | 0.71 | ACHE (0.57) | ACHEGRIN1GRIN2ABCHE | |
| SCHEMBL9736603 | 0.71 | ACHE (0.62) | ACHEGRIN1GRIN2ABCHEKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268871-A1 | Quinoline derivatives | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1988-06-01 | — | — | EP | disclosed |