Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.50 |
| ▸ | PIM1 | P11309 | 3/20 | 0.46 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10651486 | 0.83 | PTGS2 (0.43) | NPSR1ALDH1A1KDM4EKMT2AHPGD | |
| SCHEMBL10656112 | 0.82 | ALDH1A1 (0.50) | NPSR1ALDH1A1KDM4EKMT2AHPGD | |
| SCHEMBL10652386 | 0.80 | GRIA2 (0.42) | ALDH1A1KMT2APTGS2MAPTMEN1 | |
| SCHEMBL13991789 | 0.78 | PRKCZ (0.47) | NPSR1ALDH1A1KDM4EKMT2AHPGD | |
| SCHEMBL10653117 | 0.77 | ABL1 (0.40) | PTGS2PRKCZADORA1 | |
| SCHEMBL15629589 | 0.77 | PRKCZ (0.68) | NPSR1ALDH1A1KDM4EKMT2AHPGD | |
| SCHEMBL10656103 | 0.74 | ALDH1A1 (0.52) | NPSR1ALDH1A1KDM4EKMT2AHPGD | |
| SCHEMBL10656293 | 0.73 | PRKCZ (0.43) | NPSR1ALDH1A1KDM4EKMT2AHPGD | |
| SCHEMBL10654899 | 0.73 | KDM4E (0.43) | NPSR1ALDH1A1KDM4EKMT2AHPGD | |
| SCHEMBL10653342 | 0.73 | ATM (0.51) | NPSR1ALDH1A1KDM4EKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273602-A1 | 3-Cyano-4-arylthiophenes | ELI LILLY AND COMPANY (US) | 1988-07-06 | — | — | EP | disclosed |