Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1524584 | 0.79 | KDM4E (0.33) | ALDH1A1POLB | |
| SCHEMBL13425959 | 0.78 | ADORA2A (0.31) | ADORA2AADORA1 | |
| SCHEMBL8944768 | 0.77 | — | — | |
| SCHEMBL27952254 | 0.77 | NCF1 (0.39) | ADORA2AADORA1DYRK1AALDH1A1POLB | |
| N4-Hydroxycytosine SCHEMBL48396 | 0.77 | — | — | |
| SCHEMBL15798504 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL6853662 | 0.75 | NCF1 (0.38) | ADORA2AADORA1DYRK1AALDH1A1POLB | |
| SCHEMBL30917959 | 0.75 | NCF1 (0.38) | ADORA2AADORA1DYRK1AALDH1A1POLB | |
| SCHEMBL8080125 | 0.73 | ADORA2A (0.35) | ADORA2AADORA1DYRK1A | |
| SCHEMBL6853931 | 0.73 | ROCK2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999051761-A1 | IMPROVEMENTS IN OR RELATING TO NUCLEIC ACID SYNTHESIS AND SELECTION | MEDICAL RESEARCH COUNCIL (GB) | 1999-10-14 | — | — | WO | claimed |
| EP-0439550-A4 | DNA SEQUENCING BY MULTIPLE MIXED OLIGONUCLEOTIDE PROBES | — | 1991-09-25 | — | — | EP | claimed |
| EP-0439550-A1 | DNA SEQUENCING BY MULTIPLE MIXED OLIGONUCLEOTIDE PROBES | DNAX RESEARCH INSTITUTE OF MOLECULAR AND CELLULAR BIOLOGY, INC. (US) | 1991-08-07 | — | — | EP | claimed |
| WO-1990004652-A1 | DNA SEQUENCING BY MULTIPLE MIXED OLIGONUCLEOTIDE PROBES | DNAX RESEARCH INSTITUTE OF MOLECULAR AND CELLULAR BIOLOGY, INC. (US) | 1990-05-03 | — | — | WO | claimed |
| US-20250101497-A1 | Thermostable RNA Polymerase | WAGENINGEN UNIVERSITEIT (NL) | 2025-03-27 | — | — | US | disclosed |
| EP-4466343-A1 | THERMOSTABLE RNA POLYMERASE | Wageningen Universiteit (NL) | 2024-11-27 | — | — | EP | disclosed |
| EP-3959335-B1 | METHODS AND COMPOSITIONS FOR ISOTHERMAL DNA AMPLIFICATION | SYNVOLUX IP BV (NL) | 2024-09-25 | — | — | EP | disclosed |
| WO-2023140731-A1 | THERMOSTABLE RNA POLYMERASE | WAGENINGEN UNIVERSITEIT (NL) | 2023-07-27 | — | — | WO | disclosed |
| CN-116059182-A | Nanoparticle, and preparation method and application thereof | 荣灿生物医药技术(上海)有限公司 | 2023-05-05 | — | — | CN | disclosed |
| US-20220213538-A1 | Methods and Compositions for Isothermal DNA Amplification | SYNVOLUX IP B.V. (NL) | 2022-07-07 | — | — | US | disclosed |
| EP-3959335-A1 | METHODS AND COMPOSITIONS FOR ISOTHERMAL DNA AMPLIFICATION | Synvolux IP B.V. (NL) | 2022-03-02 | — | — | EP | disclosed |
| CN-114072521-A | Methods and compositions for isothermal DNA amplification | 辛沃鲁克斯IP有限公司 | 2022-02-18 | — | — | CN | disclosed |
| US-20100292471-A1 | PEPTIDE NUCLEIC ACID OLIGOMERS COMPRISING UNIVERSAL BASES,PREPARATION METHODS THEREOF, AND KITS, DEVICES AND METHODS FOR THE ANALYSIS, DETECTION OR MODULATION OF NUCLEIC ACIDS USING THE SAME | PANAGENE INC. (KR) | 2010-11-18 | — | — | US | disclosed |
| US-20100292471-A1 | PEPTIDE NUCLEIC ACID OLIGOMERS COMPRISING UNIVERSAL BASES,PREPARATION METHODS THEREOF, AND KITS, DEVICES AND METHODS FOR THE ANALYSIS, DETECTION OR MODULATION OF NUCLEIC ACIDS USING THE SAME | PANAGENE INC. (KR) | 2010-11-18 | — | — | US | disclosed |
| EP-2094863-A1 | PEPTIDE NUCLEIC ACID OLIGOMERS COMPRISING UNIVERSAL BASES, PREPARATION METHODS THEREOF, AND KITS, DEVICES AND METHODS FOR THE ANALYSIS, DETECTION OR MODULATION OF NUCLEIC ACIDS USING THE SAME | Panagene, Inc. (KR) | 2009-09-02 | — | — | EP | disclosed |
| US-20080233557-A1 | PNA Probes, Kits, and Methods for Detecting Lamivudine-Resistant Hepatitis B Viruses | PANAGENE INC. (KR) | 2008-09-25 | — | — | US | disclosed |
| WO-2008075871-A1 | PEPTIDE NUCLEIC ACID OLIGOMERS COMPRISING UNIVERSAL BASES, PREPARATION METHODS THEREOF, AND KITS, DEVICES AND METHODS FOR THE ANALYSIS, DETECTION OR MODULATION OF NUCLEIC ACIDS USING THE SAME | PANAGENE INC. (KR) | 2008-06-26 | — | — | WO | disclosed |
| WO-2004042078-A1 | NUCLEOTIDE SEQUENCE ANALYSIS BY QUANTIFICATION OF MUTAGENESIS | THE UNIVERSITY OF QUEENSLAND (AU) | 2004-05-21 | — | — | WO | disclosed |
| WO-1999051761-A1 | IMPROVEMENTS IN OR RELATING TO NUCLEIC ACID SYNTHESIS AND SELECTION | MEDICAL RESEARCH COUNCIL (GB) | 1999-10-14 | — | — | WO | disclosed |
| US-5221609-A | Molecular genetic probe, and method of forming same, assay technique and kit using said molecular genetic probe | ORGENICS LTD. (IL) | 1993-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080233557-A1 | PNA Probes, Kits, and Methods for Detecting Lamivudine-Resistant Hepatitis B Viruses | POLM, RNPEP, PNP | ADORA2A 2637/4885ADORA1 1314/4885EIF2AK2 560/4885 |
| US-20100292471-A1 | PEPTIDE NUCLEIC ACID OLIGOMERS COMPRISING UNIVERSAL BASES,PREPARATION METHODS THEREOF, AND KITS, DEVICES AND METHODS FOR THE ANALYSIS, DETECTION OR MODULATION OF NUCLEIC ACIDS USING THE SAME | ADAR, POLM, POLRMT | ADORA2A 851/4885ADORA1 646/4885EIF2AK2 266/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.