Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 7/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10743323 | 0.72 | LMNA (0.42) | GRIN2B | |
| SCHEMBL30101003 | 0.70 | TAAR1 (0.51) | TAAR1HTR1ADRD2HTR7 | |
| SCHEMBL4894264 | 0.70 | TSHR (0.51) | TAAR1 | |
| SCHEMBL13344500 | 0.69 | TAAR1 (0.39) | TAAR1HTR1ADRD2HTR7 | |
| SCHEMBL21962476 | 0.69 | DRD2 (0.43) | DRD2GRIN2BAKR1C3ACE | |
| SCHEMBL15083644 | 0.68 | SMN1; SMN2 (0.33) | TAAR1HTR1ADRD2HTR7 | |
| SCHEMBL13770917 | 0.68 | — | — | |
| SCHEMBL10745249 | 0.68 | SIRT1 (0.34) | — | |
| SCHEMBL7609208 | 0.66 | KMT2A (0.43) | TAAR1HTR1ADRD2HTR7 | |
| SCHEMBL28681399 | 0.66 | HHAT (0.46) | DRD2ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4649153-A | ANTIINFLAMMATORY, ANALGESICS | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1987-03-10 | — | — | US | claimed |
| EP-0172041-B1 | 5,6-DIHYDRO-4H-CYCLOPENTA(B)THIOPHENE-6-CARBOXYLIC ACIDS, PROCESSES FOR THEIR PREPARATION AND THERAPEUTICAL AGENTS CONTAINING THEM | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1988-08-10 | — | — | EP | disclosed |
| US-4649153-A | ANTIINFLAMMATORY, ANALGESICS | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1987-03-10 | — | — | US | disclosed |
| US-4649153-A | ANTIINFLAMMATORY, ANALGESICS | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1987-03-10 | — | — | US | disclosed |
| EP-0172041-A1 | 5,6-Dihydro-4H-cyclopenta(b)thiophene-6-carboxylic acids, processes for their preparation and therapeutical agents containing them | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1986-02-19 | — | — | EP | disclosed |