Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PNMT | P11086 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | FABP4 | P15090 | 1/20 | 0.31 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7606949 | 0.79 | SIRT1 (0.32) | SIRT1GFERHSD17B10 | |
| SCHEMBL10746503 | 0.79 | POLB (0.34) | HSD17B10KDM4EALDH1A1MAPK1MAPT | |
| SCHEMBL10742143 | 0.75 | ALDH1A1 (0.34) | ALDH1A1POLB | |
| SCHEMBL10754496 | 0.72 | TBXAS1 (0.32) | POLB | |
| SCHEMBL17970193 | 0.68 | UGT2B17 (0.40) | PNMTALDH1A1POLB | |
| SCHEMBL10653698 | 0.68 | TAAR1 (0.37) | — | |
| SCHEMBL10741469 | 0.68 | HSD17B2 (0.33) | GFERHSD17B10RXFP1LMNAKDM4E | |
| SCHEMBL19642816 | 0.67 | SIRT1 (0.41) | SIRT1HSD17B10ALDH1A1MAPT | |
| SCHEMBL19643822 | 0.67 | SIRT1 (0.41) | SIRT1HSD17B10ALDH1A1MAPT | |
| SCHEMBL13303500 | 0.67 | UGT2B17 (0.35) | PNMTLMNAALDH1A1PKMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4649153-A | ANTIINFLAMMATORY, ANALGESICS | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1987-03-10 | — | — | US | disclosed |