Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.70 |
| ▸ | HPGD | P15428 | 7/20 | 0.70 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.70 |
| ▸ | POLB | P06746 | 3/20 | 0.70 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.70 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.70 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.70 |
| ▸ | CLK2 | P49760 | 1/20 | 0.70 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.70 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.65 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.65 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.65 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8433684 | 0.94 | ALDH1A1 (0.77) | ALDH1A1KDM4EHPGDKCNH2HSD17B10 | |
| Hydrochloric Acid SCHEMBL10914782 | 0.93 | ALDH1A1 (0.76) | ALDH1A1KDM4EHPGDKCNH2HSD17B10 | |
| SCHEMBL10647154 | 0.90 | KDM4E (0.58) | ALDH1A1KDM4EHPGDKCNH2HSD17B10 | |
| SCHEMBL29593740 | 0.86 | ALDH1A1 (0.81) | ALDH1A1KDM4EHPGDKCNH2HSD17B10 | |
| SCHEMBL6783172 | 0.86 | ALDH1A1 (0.81) | ALDH1A1KDM4EHPGDKCNH2HSD17B10 | |
| SCHEMBL8435331 | 0.85 | ALDH1A1 (0.66) | ALDH1A1KDM4EHPGDKCNH2HSD17B10 | |
| SCHEMBL9626969 | 0.85 | ALDH1A1 (0.63) | ALDH1A1KDM4EHPGDKCNH2HSD17B10 | |
| SCHEMBL3957125 | 0.84 | ALDH1A1 (0.79) | ALDH1A1KDM4EHPGDKCNH2HSD17B10 | |
| SCHEMBL9792010 | 0.84 | KCNH2 (0.79) | ALDH1A1KDM4EHPGDKCNH2HSD17B10 | |
| SCHEMBL965845 | 0.84 | ALDH1A1 (0.70) | ALDH1A1KDM4EHPGDKCNH2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0164619-B1 | 2,4,5-TRIHALO OR 2,3,4,5-TETRAHALO BENZENE DERIVATIVES AND PROCESS FOR PRODUCING THEM | BAYER AG (DE) | 1988-10-12 | — | — | EP | disclosed |
| EP-0167763-A1 | 7-Amino-1-cyclopropyl-6,8-dihalo-1,4-dihydro-4-oxo-3-quinoline-carboxylic acids, process for their preparation and bactericidal agents containing them | BAYER AG (DE) | 1986-01-15 | — | — | EP | disclosed |
| EP-0164619-A1 | 2,4,5-Trihalo or 2,3,4,5-tetrahalo benzene derivatives and process for producing them | BAYER AG (DE) | 1985-12-18 | — | — | EP | disclosed |