Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10653357 | 0.89 | MAPT (0.41) | LTA4HLMNAMAPTFDPSBCHE | |
| SCHEMBL27824326 | 0.86 | KCNH2 (0.41) | LTA4HLMNAMAPTALDH1A1HTT | |
| SCHEMBL10656175 | 0.85 | L3MBTL1 (0.43) | L3MBTL1LTA4HALOX15LMNAMAPT | |
| SCHEMBL1416062 | 0.81 | KMT2A (0.34) | L3MBTL1LTA4HALOX15LMNATSHR | |
| SCHEMBL10655415 | 0.81 | HPGD (0.35) | L3MBTL1LMNAALDH1A1 | |
| SCHEMBL4528090 | 0.80 | ALOX5 (0.44) | ALOX5BCHE | |
| SCHEMBL1416171 | 0.77 | KMT2A (0.33) | L3MBTL1LTA4HALOX15LMNATSHR | |
| SCHEMBL10656155 | 0.76 | LMNA (0.35) | LMNAMAPTHSD17B10ALDH1A1 | |
| SCHEMBL27727484 | 0.76 | PPARA (0.41) | LTA4HALOX15MAPTALDH1A1 | |
| SCHEMBL26130465 | 0.75 | ALOX5 (0.40) | TSHRALOX5BCHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0177740-B1 | ACYLATED SACCHARINE DERIVATIVES | BAYER AG (DE) | 1988-09-28 | — | — | EP | claimed |
| US-4713389-A | Fungicidally and bactericidally active acylated saccharin derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1987-12-15 | — | — | US | claimed |
| EP-0177740-A1 | Acylated saccharine derivatives | BAYER AG (DE) | 1986-04-16 | — | — | EP | claimed |
| EP-0177740-B1 | ACYLATED SACCHARINE DERIVATIVES | BAYER AG (DE) | 1988-09-28 | — | — | EP | disclosed |
| US-4713389-A | Fungicidally and bactericidally active acylated saccharin derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1987-12-15 | — | — | US | disclosed |
| EP-0177740-A1 | Acylated saccharine derivatives | BAYER AG (DE) | 1986-04-16 | — | — | EP | disclosed |