Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | LAP3 | P28838 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | FPR1 | P21462 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10655415 | 0.86 | HPGD (0.35) | LMNAAOC3ANPEPLAP3HPGD | |
| SCHEMBL10656175 | 0.79 | L3MBTL1 (0.43) | LMNAALDH1A1HSD17B10MAPT | |
| SCHEMBL10654697 | 0.76 | L3MBTL1 (0.37) | LMNAALDH1A1HSD17B10MAPT | |
| SCHEMBL1416171 | 0.76 | KMT2A (0.33) | LMNAALDH1A1 | |
| SCHEMBL10653357 | 0.74 | MAPT (0.41) | LMNAMAPT | |
| SCHEMBL1416062 | 0.73 | KMT2A (0.34) | LMNA | |
| SCHEMBL14855357 | 0.73 | ALOX15 (0.42) | — | |
| SCHEMBL4528090 | 0.71 | ALOX5 (0.44) | AOC3 | |
| SCHEMBL27824326 | 0.71 | KCNH2 (0.41) | LMNAALDH1A1MAPT | |
| SCHEMBL8128151 | 0.69 | ALDH1A1 (0.39) | LMNAAOC3ALDH1A1FPR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0177740-B1 | ACYLATED SACCHARINE DERIVATIVES | BAYER AG (DE) | 1988-09-28 | — | — | EP | claimed |
| US-4713389-A | Fungicidally and bactericidally active acylated saccharin derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1987-12-15 | — | — | US | claimed |
| EP-0177740-A1 | Acylated saccharine derivatives | BAYER AG (DE) | 1986-04-16 | — | — | EP | claimed |
| EP-0177740-B1 | ACYLATED SACCHARINE DERIVATIVES | BAYER AG (DE) | 1988-09-28 | — | — | EP | disclosed |
| US-4713389-A | Fungicidally and bactericidally active acylated saccharin derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1987-12-15 | — | — | US | disclosed |
| EP-0177740-A1 | Acylated saccharine derivatives | BAYER AG (DE) | 1986-04-16 | — | — | EP | disclosed |