Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10654697 | 0.85 | L3MBTL1 (0.37) | L3MBTL1LMNAHTTLTA4HALDH1A1 | |
| SCHEMBL10653357 | 0.82 | MAPT (0.41) | LMNAHTTLTA4HMAPTKMT2A | |
| SCHEMBL1416171 | 0.80 | KMT2A (0.33) | L3MBTL1LMNASMN1; SMN2LTA4HALDH1A1 | |
| SCHEMBL10656155 | 0.79 | LMNA (0.35) | LMNAALDH1A1MAPTHSD17B10 | |
| SCHEMBL27824326 | 0.79 | KCNH2 (0.41) | LMNAHTTSMN1; SMN2LTA4HALDH1A1 | |
| SCHEMBL1416062 | 0.77 | KMT2A (0.34) | L3MBTL1LMNASMN1; SMN2LTA4HTSHR | |
| SCHEMBL14855357 | 0.77 | ALOX15 (0.42) | L3MBTL1SMN1; SMN2ALOX15MAPK1 | |
| SCHEMBL10655415 | 0.77 | HPGD (0.35) | L3MBTL1LMNASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL4528090 | 0.76 | ALOX5 (0.44) | NPC1RAB9AGAAKMT2A | |
| SCHEMBL1573556 | 0.73 | TSHR (0.40) | L3MBTL1LMNAALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0177740-B1 | ACYLATED SACCHARINE DERIVATIVES | BAYER AG (DE) | 1988-09-28 | — | — | EP | claimed |
| US-4713389-A | Fungicidally and bactericidally active acylated saccharin derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1987-12-15 | — | — | US | claimed |
| EP-0177740-A1 | Acylated saccharine derivatives | BAYER AG (DE) | 1986-04-16 | — | — | EP | claimed |
| EP-0177740-B1 | ACYLATED SACCHARINE DERIVATIVES | BAYER AG (DE) | 1988-09-28 | — | — | EP | disclosed |
| US-4713389-A | Fungicidally and bactericidally active acylated saccharin derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1987-12-15 | — | — | US | disclosed |
| EP-0177740-A1 | Acylated saccharine derivatives | BAYER AG (DE) | 1986-04-16 | — | — | EP | disclosed |