Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.68 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.64 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.64 |
| ▸ | HSPA9 | P38646 | 1/20 | 0.64 |
| ▸ | HSPA2 | P54652 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | HPGDS | O60760 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.55 |
| ▸ | MME | P08473 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | ACE | P12821 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10654990 | 1.00 | CTSL (0.68) | CTSLHSPA1AHSPA5HSPA9HSPA2 | |
| SCHEMBL16993982 | 0.90 | CTSL (0.57) | CTSLHSPA1AHSPA5HSPA9HSPA2 | |
| SCHEMBL16993875 | 0.90 | CTSL (0.57) | CTSLHSPA1AHSPA5HSPA9HSPA2 | |
| SCHEMBL15689516 | 0.85 | CTSL (0.55) | CTSLHSPA1AHSPA5HSPA9HSPA2 | |
| SCHEMBL11386076 | 0.84 | RAB9A (0.54) | CTSLHSPA1AHSPA5HSPA9HSPA2 | |
| SCHEMBL9705401 | 0.84 | RAB9A (0.54) | CTSLHSPA1AHSPA5HSPA9HSPA2 | |
| SCHEMBL9705400 | 0.84 | RAB9A (0.54) | CTSLHSPA1AHSPA5HSPA9HSPA2 | |
| SCHEMBL8144685 | 0.83 | HSPA5 (0.61) | CTSLHSPA1AHSPA5HSPA9HSPA2 | |
| SCHEMBL16375213 | 0.83 | HSPA1A (0.53) | CTSLHSPA1AHSPA5HSPA9HSPA2 | |
| SCHEMBL24862855 | 0.82 | HPGD (0.77) | CTSLHSPA1AHSPA5HSPA9HSPA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3102193-B1 | ANTIBACTERIAL AGENTS: N(ALPHA)-AROYL-N-ARYL-PHENYLALANINAMIDES | UNIV RUTGERS (US) | 2023-01-11 | — | — | EP | disclosed |
| WO-2020014726-A1 | TREATMENT FOR LIVER REGENERATION | XENEXUS PHARMACEUTICALS PTY. LTD. (AU) | 2020-01-23 | — | — | WO | disclosed |
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |
| EP-3102193-A1 | ANTIBACTERIAL AGENTS: N(ALPHA)-AROYL-N-ARYL-PHENYLALANINAMIDES | Rutgers, The State University of New Jersey (US) | 2016-12-14 | — | — | EP | disclosed |
| US-20160347708-A1 | ANTIBACTERIAL AGENTS: N(ALPHA)-AROYL-N-ARYL-PHENYLALANINAMIDES | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2016-12-01 | — | — | US | disclosed |
| WO-2015120320-A1 | ANTIBACTERIAL AGENTS: N(ALPHA)-AROYL-N-ARYL-PHENYLALANINAMIDES | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2015-08-13 | — | — | WO | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160347708-A1 | ANTIBACTERIAL AGENTS: N(ALPHA)-AROYL-N-ARYL-PHENYLALANINAMIDES | TYR, NAT1, AANAT | CTSL 447/4885HSPA1A 1715/4885HSPA5 2539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.