Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 3/20 | 0.38 |
| ▸ | FNTB | P49356 | 3/20 | 0.38 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.38 |
| ▸ | SQOR | Q9Y6N5 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10653113 | 0.90 | ALDH1A1 (0.41) | ALOX5PTGS2HPGDKDM4EALDH1A1 | |
| SCHEMBL10655134 | 0.84 | KDM4E (0.43) | ALOX5PTGS2HPGDKDM4EALDH1A1 | |
| SCHEMBL10654581 | 0.75 | KDM4E (0.51) | ALOX5PTGS2HPGDKDM4EALDH1A1 | |
| SCHEMBL10653153 | 0.73 | ALOX5 (0.42) | ALOX5PTGS2HPGDKDM4EALDH1A1 | |
| SCHEMBL10655996 | 0.73 | ALOX5 (0.39) | ALOX5PTGS2HPGDKDM4EALDH1A1 | |
| SCHEMBL10651771 | 0.73 | KDM4E (0.40) | PTGS2HPGDKDM4EALDH1A1TDP1 | |
| SCHEMBL10654580 | 0.72 | CYP2A6 (0.40) | HPGDKDM4EALDH1A1LMNANPSR1 | |
| SCHEMBL4259769 | 0.72 | PRKCZ (0.56) | ALOX5PTGS2HPGDKDM4EALDH1A1 | |
| SCHEMBL10654927 | 0.71 | KDM4E (0.40) | ALOX5PTGS2HPGDKDM4EALDH1A1 | |
| SCHEMBL10653878 | 0.70 | ADORA1 (0.43) | HPGDKDM4EALDH1A1TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273602-A1 | 3-Cyano-4-arylthiophenes | ELI LILLY AND COMPANY (US) | 1988-07-06 | — | — | EP | disclosed |