Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 2/20 | 0.49 |
| ▸ | TNF | P01375 | 2/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.41 |
| ▸ | MGLL | Q99685 | 3/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | PDE4A | P27815 | 3/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4156451 | 0.95 | PDE4A (0.43) | ADORA2BTNFPDE4AADORA2APDE4B | |
| SCHEMBL4150749 | 0.84 | PDE4A (0.42) | ADORA2BCYP1A2CYP2C19PDE4AADORA2A | |
| SCHEMBL4146972 | 0.84 | ADORA2B (0.40) | ADORA2BPTGS1PTGS2MGLLFAAH | |
| SCHEMBL19148089 | 0.82 | ALDH1A1 (0.53) | ADORA2BTNFPTGS1PTGS2MGLL | |
| SCHEMBL19147853 | 0.82 | ALDH1A1 (0.53) | ADORA2BTNFPTGS1PTGS2MGLL | |
| SCHEMBL19147865 | 0.82 | ALDH1A1 (0.53) | ADORA2BTNFPTGS1PTGS2MGLL | |
| SCHEMBL10656238 | 0.80 | ALDH1A1 (0.52) | ADORA2BTNFPTGS1PTGS2MGLL | |
| SCHEMBL4146852 | 0.79 | TDP1 (0.40) | ADORA2BPDE4AADORA2APDE4BPDE4C | |
| SCHEMBL28439331 | 0.73 | PTGS1 (0.41) | PTGS1PTGS2MGLLFAAHTLR8 | |
| SCHEMBL28435216 | 0.73 | PTGS1 (0.41) | PTGS1PTGS2MGLLFAAHTLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1318168-A1 | Stabiliser combinations for chlorinated polymers | Crompton Vinyl Additives GmbH (DE) | 2003-06-11 | — | — | EP | disclosed |